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Doxepin

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Identification
Molecular formula
C19H21NO2
CAS number
1668-19-5
IUPAC name
6-[3-(dimethylamino)propyl]-5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin-11-ol
State
State
At room temperature, doxepin is in a solid state.
Melting point (Celsius)
196.50
Melting point (Kelvin)
469.60
Boiling point (Celsius)
445.20
Boiling point (Kelvin)
718.20
General information
Molecular weight
279.38g/mol
Molar mass
279.3750g/mol
Density
1.2910g/cm3
Appearence

Doxepin appears as a white to off-white crystalline powder. It is typically found in its hydrochloride salt form for pharmaceutical applications.

Comment on solubility

Solubility of 6-[3-(dimethylamino)propyl]-5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin-11-ol

The solubility of 6-[3-(dimethylamino)propyl]-5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin-11-ol can be influenced by several factors including the compound's structure, polarity, and the solvent used. Key points to consider are:

  • Polarity: This compound contains both hydrophobic and hydrophilic regions, which may affect its ability to dissolve in various solvents.
  • Solvent Interaction: It is likely to show better solubility in organic solvents than in water, given its complex structure.
  • pH Sensitivity: The solubility may vary with pH changes, suggesting an interaction with acidic or basic conditions.
  • Structural Factors: The presence of the dimethylamino group may enhance solubility due to its basic nature, potentially increasing interactions with polar solvents.

Research and testing are essential to accurately determine the solubility profile. As stated in the field, "Like dissolves like," which emphasizes the importance of considering both chemical structure and solvent properties when assessing solubility.

In conclusion, understanding the solubility of this compound is crucial for its applications, and it is recommended to conduct further studies to explore its behavior in different solvents.

Interesting facts

Interesting Facts About 6-[3-(Dimethylamino)propyl]-5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin-11-ol

This compound, also known for its complex structure, is often associated with unique pharmacological properties. Below are some intriguing insights into this remarkable chemical:

  • Pharmacological Interest: This compound has been studied for its potential use in medicinal chemistry, particularly in developing treatments for various neurological disorders. The presence of the dimethylamino group may contribute to its activity by enhancing interactions with biological targets.
  • Molecular Complexity: The structure of this compound includes multiple fused rings and a thiophene moiety, which are characteristic of many bioactive compounds. Such structural intricacies can lead to unique modes of action within biological systems.
  • Potential Applications: Compounds like this one are investigated for their roles in psychiatric medications due to their ability to modulate neurotransmitter pathways.
  • Research Implications: Ongoing studies into similar compounds often focus on optimizing their structures to improve efficacy and reduce side effects, showcasing the dynamic nature of drug discovery.

In summary, the intriguing aspects of 6-[3-(dimethylamino)propyl]-5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin-11-ol highlight its potential in medicinal chemistry. As research evolves, this compound may reveal even more distinctive properties that could pave the way for innovative therapeutic solutions.