Skip to main content

Desipramine

ADVERTISEMENT
Identification
Molecular formula
C18H22N2O
CAS number
50-47-5
IUPAC name
6-[3-(dimethylamino)propyl]-7H-benzo[d][2]benzazepin-5-one
State
State

At room temperature, desipramine is generally found in a solid state. It is not volatile and does not readily evaporate.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
359.10
Boiling point (Kelvin)
632.25
General information
Molecular weight
294.40g/mol
Molar mass
294.3960g/mol
Density
1.1400g/cm3
Appearence

Desipramine is typically a white or off-white crystalline solid. It may also be available in the form of a powder. The appearance can vary slightly based on the presence of impurities or the specific form (e.g., salt) in which it is delivered.

Comment on solubility

Solubility of 6-[3-(dimethylamino)propyl]-7H-benzo[d][2]benzazepin-5-one

The solubility of 6-[3-(dimethylamino)propyl]-7H-benzo[d][2]benzazepin-5-one can be influenced by various factors, making it necessary to examine its interactions with solvents comprehensively. This compound, belonging to the category of heterocyclic compounds, often shows variable solubility in different media.

  • Polar solvents: Generally, due to the presence of the dimethylamino group, the compound may exhibit moderate solubility in polar solvents like water and methanol. The ability of the dimethylamino group to form hydrogen bonds enhances its solubility in such environments.
  • Non-polar solvents: Conversely, in less polar or non-polar solvents, its solubility may decrease significantly. Solvents such as hexane or chloroform could exhibit poor solubility characteristics for this compound, reflecting its structural complexity.

When considering practical applications, it is important to note that the solvent choice can have substantial implications on the efficacy and stability of this compound. Thus, *testing solubility in various environments is crucial* to determine the optimal conditions for its use. Understanding these solubility characteristics allows for better utilization in pharmacological or chemical processes.

Overall, the solubility of 6-[3-(dimethylamino)propyl]-7H-benzo[d][2]benzazepin-5-one is a key factor that warrants close examination in its chemical analysis and application development.

Interesting facts

Interesting Facts about 6-[3-(dimethylamino)propyl]-7H-benzo[d][2]benzazepin-5-one

This compound, known for its complex structure, is a member of the benzazepine family, which is a class of heterocyclic organic compounds. These compounds have been of significant interest in medicinal chemistry due to their various pharmacological properties.

Key Characteristics:

  • Pharmacological Potential: Compounds like this one have been researched for their potential use in treating disorders such as depression and anxiety, highlighting their significance in mental health therapies.
  • Structural Complexity: The presence of both a benzene and an azepine ring system contributes to the compound's intriguing chemical behavior, allowing for a variety of interactions with biological targets.
  • Dimethylamino Group: The dimethylamino substituent is known to enhance the compound's lipophilicity, which can facilitate its passage across cell membranes, potentially increasing its efficacy.

In a broader context, benzazepines represent an important class of compounds with various substitutions leading to a wide range of biological activities. As mentioned in studies, structures like this compound can lead to the design of novel drugs with improved specificity and fewer side effects.

Did You Know?

  • The use of benzazepines in drug design exemplifies how structure-activity relationship (SAR) studies guide the development of new therapeutic agents.
  • Benzazepines have also been influential in the study of signal transduction pathways, especially regarding neurotransmitter activity in the central nervous system.
  • Ongoing research keeps unveiling new pharmaceutical applications, making compounds like this one an exciting area of investigation for chemists and pharmacologists alike.

This compound symbolizes the profound intersection of chemistry and medicine, reminding us that the intricacies of molecular structures can have significant implications in developing new therapies and understanding biological processes.