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Dihydrouridine

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Identification
Molecular formula
C9H14N2O5
CAS number
5620-54-0
IUPAC name
6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione
State
State

At room temperature, dihydrouridine is a solid. It is stable under normal conditions of use and storage, but as with all chemicals, it should be handled with care to avoid moisture absorption and degradation.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
234.50
Boiling point (Kelvin)
507.60
General information
Molecular weight
216.20g/mol
Molar mass
216.1970g/mol
Density
1.5000g/cm3
Appearence

Dihydrouridine typically appears as a white to off-white crystalline powder. It is often synthesized and used in a laboratory setting, where its specific visuals can depend on its form and the presence of any additives or impurities.

Comment on solubility

Solubility of 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione

The solubility of the compound 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione (C9H14N2O5) is an intriguing aspect that deserves attention. Solubility is governed by several factors, including molecular structure, intermolecular forces, and environmental conditions. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl (-OH) groups suggests that the compound is likely to exhibit polar characteristics, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The compound's structure may promote effective hydrogen bonding with solvents, aiding in its dissolution. "Hydrogen bonds enhance solubility in polar environments."
  • Solvent Compatibility: While it may be soluble in water due to its hydroxyl groups, it could be less soluble in non-polar solvents due to hydrophobic methyl groups.
  • Temperature and pH: Solubility can also vary with temperature and the pH of the solution, potentially leading to increased solubility or precipitation depending on the conditions.

In conclusion, the solubility characteristics of 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione make it a compound of interest, particularly for applications that require specific solubility profiles. Further experimental data would be necessary to quantify its solubility under various conditions.

Interesting facts

Exploring 6-[3-Hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione

6-[3-Hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione, with its complex structure, is a fascinating compound in the realm of organic chemistry. Here are some intriguing facts about this compound:

  • Biological Significance: This pyrimidine derivative is known to possess biological activity, which has made it a subject of interest in medicinal chemistry.
  • Structural Attributes: The presence of both hydroxy and hydroxymethyl groups within its structure contributes to its diverse reactivity and potential applications.
  • Potential Drug Development: Due to its structural components, there is ongoing research into its potential use in pharmaceutical applications, particularly in the development of new therapeutic agents.
  • Complex Chemistry: The multifunctional nature of this compound allows for various chemical transformations, which makes it an excellent candidate for synthetic organic chemistry exploration.
  • Historical Context: Compounds like this one are often explored for their role in biological processes, such as enzyme regulation and as intermediates in metabolic pathways.

As chemists delve deeper into the unique properties of 6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione, they may uncover more about how such compounds can influence human health and disease. The ongoing study of its structure and function continues to inspire innovation in the realm of biochemical research.

Synonyms
6-(DIHYDROXY-ISOBUTYL)-THYMINE
DHBT
6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-2,4(1h,3h)-pyrimidinedione
6-(1,3-dihydroxyisobutyl)thymine
6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methylpyrimidine-2,4(1H,3H)-dione
6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-1H-pyrimidine-2,4-dione
6-[3-hydroxy-2-(hydroxymethyl)propyl]thymine
CCV
6-(Dihydroxyisobutyl)-Thymine
SCHEMBL21067903
CHEBI:41485
DB02500
PD007919
NS00068867
Q27093487