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Trimebutine

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Identification
Molecular formula
C17H25NO5
CAS number
39133-31-2
IUPAC name
6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid
State
State

This compound is a solid at room temperature, existing primarily in its stable crystalline form.

Melting point (Celsius)
123.50
Melting point (Kelvin)
396.65
Boiling point (Celsius)
465.90
Boiling point (Kelvin)
739.05
General information
Molecular weight
311.35g/mol
Molar mass
311.3490g/mol
Density
1.2000g/cm3
Appearence

6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid typically appears as a white to off-white crystalline powder. It is a relatively stable chemical compound when stored in its appropriate conditions.

Comment on solubility

Solubility of 6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid

The solubility of 6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid can be influenced by various factors, including its molecular structure and the nature of solvents. This compound, characterized by both hydrophobic and hydrophilic segments, exhibits unique solubility properties:

  • Polar solvents: Its ability to interact with polar solvents, such as water, may be limited due to the significant hydrophobic characteristics imparted by the trimethoxybenzoyl moiety.
  • Non-polar solvents: Conversely, it is more likely to dissolve in non-polar or weakly polar solvents due to the presence of long hydrocarbon chains which enhance its interaction with similar solvent types.
  • Temperature effects: Solubility can also be temperature-dependent; generally, higher temperatures can lead to increased solubility for many organic compounds.
  • pH sensitivity: Being an amino acid derivative, its solubility may vary with pH changes in the solution, which can affect the ionization of the carboxylic acid and amine groups.

Therefore, while 6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid may demonstrate moderate solubility in certain organic solvents, it is essential to consider the interplay of solvent characteristics, temperature, and pH conditions for its practical use.

Interesting facts

Interesting Facts about 6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid

6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid is a fascinating compound that combines both biochemical and pharmaceutical significance. Here are some notable aspects of this compound:

  • Structural Diversity: This compound features a unique structure that includes multiple functional groups, making it a subject of interest in medicinal chemistry. The presence of the trimethoxybenzoyl group adds an aromatic character which can influence its biological activity.
  • Biological Relevance: Compounds like this one can often serve as leads in the development of new drugs, especially in targeting specific biological pathways. The amine and carboxylic acid functionalities suggest potential for interaction with various biological receptors.
  • Implications in Drug Design: The ability of this compound to act as a synthetic analog makes it important in drug discovery research. Its structure can be modified to enhance potency, selectivity, and reduce side effects.
  • Environmental Considerations: Compounds like this may be studied for their environmental impact, especially if they are used in pharmaceuticals or agrochemicals. Understanding their breakdown and interaction with biological systems can lead to safer usage.
  • Research Interest: Due to its complex structure, it can serve as a valuable example in studies focusing on structure-activity relationships (SAR), which examines how modifications in chemical structure influence biological activity.

In summary, 6-[(3,4,5-trimethoxybenzoyl)amino]hexanoic acid holds significant promise in the fields of medicinal chemistry and therapeutic drug development. Its intriguing structure and potential applications make it an exciting compound for ongoing research.

Synonyms
CAPOBENIC ACID
21434-91-3
Trifartine
6-[(3,4,5-Trimethoxybenzoyl)amino]hexanoic acid
Acido capobenico
Acide capobenique
Acidum capobenicum
6-(3,4,5-Trimethoxybenzamido)hexanoic acid
NSC-230936
NSC-759126
DTXSID3045695
3R77T835TA
MLS000029754
DTXCID1025695
C-3
NCGC00027960-02
SMR000001015
6-(3,4,5-Trimethoxy-benzoylamino)-hexanoic acid
Hexanoic acid, 6-((3,4,5-trimethoxybenzoyl)amino)-
Pectoris
Capobenic-Acid
CAS-21434-91-3
ATBAC
SR-01000357658
6-[(3,4,5-trimethoxyphenyl)carbonylamino]hexanoic acid
C-Tre
TB-ACA
Opera_ID_1430
RefChem:1080763
CAPOBENIC ACID [MI]
Capobenic acid (USAN/INN)
CAPOBENIC ACID [INN]
Capobenic acid [USAN:INN]
MLS001240192
CAPOBENIC ACID [USAN]
SCHEMBL309384
UNII-3R77T835TA
CAPOBENIC ACID [MART.]
Acide capobenique [INN-French]
Acido capobenico [INN-Spanish]
Acidum capobenicum [INN-Latin]
CHEMBL1418182
CHEBI:135388
MPTXLVRHYGBOQY-UHFFFAOYSA-N
HMS2093H19
HMS2234H12
Pharmakon1600-01505417
EINECS 244-387-6
Tox21_110972
WLN: QV5MVR CO1 DO1 EO1
NSC230936
NSC759126
SBB015535
STK046287
AKOS000274209
Tox21_110972_1
CCG-213428
HY-W288642
NSC 230936
NSC 759126
Hexanoic acid,4,5-trimethoxybenzamido)-
NCGC00027960-03
6-(3,5-Trimethoxybenzamido)hexanoic acid
DA-49895
6-(3,4,5-Trimethoxybenzamido)hexansaeure
SBI-0206852.P001
6-(3,5-Trimethoxybenzamido) hexanoic acid
CS-0333618
Hexanoic acid,4,5-trimethoxybenzoyl)amino]-
NS00026868
ST50000077
3,5-Trimethoxybenzoyl-.xi.-aminocaproic acid
6-(3,4,5-Trimethoxybenzamido) hexanoic acid
Hexanoic acid,4,5-(trimethoxybenzoyl)amino]-
6-[(3,5-Trimethoxybenzoyl)amino]hexanoic acid
D03369
AB00396271-11
AB00396271_13
3,5-Trimethoxybenzoyl-.epsilon.-aminocaproic acid
6-[(3,4,5-trimethoxyphenyl)formamido]hexanoic acid
Q4727112
SR-01000357658-1
SR-01000357658-3
BRD-K04282412-001-16-3
N-(3,5-Trimethoxybenzoyl)-.epsilon.-aminocaproic acid
6-{[(3,4,5-trimethoxyphenyl)carbonyl]amino}hexanoic acid
244-387-6