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Erythromycin A

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
6-[(3R,4S,5S,7S)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl]-2-hydroxy-3-methyl-benzoic acid
State
State

At room temperature, Erythromycin A is a solid. It is typically available as a white, crystalline powder.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
437.00
Boiling point (Kelvin)
710.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2400g/cm3
Appearence

Erythromycin A is a white, crystalline powder and is utilized as an antibiotic. It is generally found in a dry, powdered form for pharmaceutical use. Its crystalline nature makes it appear as a fluffy powder when compacted.

Comment on solubility

Solubility of 6-[(3R,4S,5S,7S)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl]-2-hydroxy-3-methyl-benzoic acid

This compound exhibits variable solubility characteristics due to its intricate molecular structure. Factors influencing its solubility include:

  • Polarity: The presence of functional groups such as hydroxyl (-OH) and carboxylic acid (-COOH) can enhance solubility in polar solvents like water.
  • Hydrophobic regions: The extended hydrocarbon chains may lead to decreased solubility in polar solvents, making it more soluble in nonpolar solvents.
  • Temperature: As with many compounds, increasing the temperature typically increases solubility, particularly for solids in liquids.

In summary, while this compound may show notable solubility in water due to its polar functional groups, the presence of hydrophobic elements suggests it will also have a considerable degree of solubility in organic solvents. As always, understanding the specific interactions at play is crucial for predicting solubility behavior.

Interesting facts

Interesting Facts about 6-[(3R,4S,5S,7S)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl]-2-hydroxy-3-methyl-benzoic acid

This compound, known for its complex structure, is a fascinating example of the diversity of organic molecules in chemistry. With its multiple chiral centers and functional groups, it showcases the nuances of stereochemistry and molecular interaction. Here are some interesting aspects of this compound:

  • Stereochemistry: The presence of several stereocenters indicates that this compound may exhibit isomerism, which can lead to drastically different biological activities or properties.
  • Biological Significance: Compounds like this one are often studied for their potential pharmaceutical applications. The intricate structure may influence its ability to interact with biological targets.
  • Natural Products: Many similar compounds are derived from natural products, and understanding their chemistry can reveal insights about medicinal chemistry and biochemistry.
  • Reaction Pathways: The complex formation of this compound suggests various reaction pathways in organic synthesis, making it an interesting target for chemists looking to explore innovative synthetic routes.
  • Functionalization: The multiple functional groups in this molecule allow for diverse modifications, which could lead to the creation of novel compounds with unique properties.

As noted by renowned chemist Linus Pauling, "The chemistry of a compound is closely related to its structure." This statement holds true for our compound, emphasizing the importance of comprehending both structural and chemical properties when exploring potential applications.

In summary, 6-[(3R,4S,5S,7S)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl]-2-hydroxy-3-methyl-benzoic acid is more than just a chemical compound; it embodies the intricate relationships between structure, function, and the vast potential for discovery in the realm of chemistry.