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Coenzyme Q10

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Identification
Molecular formula
C59H90O4
CAS number
303-98-0
IUPAC name
6-[[4-[2-[2-[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[hydroxy-[hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl]oxy-phosphoryl]oxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-4-carboxy-butanoyl]amino]-2-amino-7-[[2-(1-carboxyethylamino)-1-methyl-2-oxo-ethyl]amino]-7-oxo-heptanoic acid
State
State

At room temperature, Coenzyme Q10 is typically a solid in the form of a crystalline powder.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
176.00
Boiling point (Kelvin)
449.15
General information
Molecular weight
863.36g/mol
Molar mass
863.3590g/mol
Density
1.8845g/cm3
Appearence

The compound typically appears as an orange-yellow crystalline powder. It is hydrophobic and lipophilic, making it insoluble in water but soluble in organic solvents like ethanol and acetone.

Comment on solubility

Solubility of 6-[[4-[2-[2-[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[hydroxy-[hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl]oxy-phosphoryl]oxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-4-carboxy-butanoyl]amino]-2-amino-7-[[2-(1-carboxyethylamino)-1-methyl-2-oxo-ethyl]amino]-7-oxo-heptanoic acid (C59H90O4)

The solubility of complex compounds like 6-[[4-[2-[2-[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[hydroxy-[hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl]oxy-phosphoryl]oxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-4-carboxy-butanoyl]amino]-2-amino-7-[[2-(1-carboxyethylamino)-1-methyl-2-oxo-ethyl]amino]-7-oxo-heptanoic acid can be quite intricate due to its large and diverse structural components.

Factors Influencing Solubility

Several factors affect the solubility of this compound:

  • Molecular Structure: The presence of multiple functional groups, such as carboxylic acids and hydroxyl groups, can enhance solubility in polar solvents.
  • Hydrophobic Regions: The long hydrocarbon chains may contribute to hydrophobic interactions, decreasing solubility in aqueous environments.
  • pH Sensitivity: The carboxylic groups in the structure may ionize at different pH levels, further influencing solubility.

Due to its complexity, one can expect that:

  • The compound may exhibit higher solubility in polar solvents such as water.
  • Solubility may decrease in non-polar solvents due to the hydrophobic components.
  • Testing under various conditions (e.g., different pH levels) could provide more precise insights into its solubility behavior.

In conclusion, the solubility of C59H90O4 is a balance of various interactions between its functional groups and the surrounding solvent, making it a fascinating subject for further study.

Interesting facts

Interesting Facts about 6-[[4-[2-[2-[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[hydroxy-[hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl]oxy-phosphoryl]oxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-4-carboxy-butanoyl]amino]-2-amino-7-[[2-(1-carboxyethylamino)-1-methyl-2-oxo-ethyl]amino]-7-oxo-heptanoic acid

This compound, with its intricate structure, represents a fascinating example of organic chemistry and biochemistry. Here are some noteworthy aspects:

  • Complex Structure: The compound features a complicated assembly of amino acids, sugar moieties, and phosphorothioate groups, highlighting the incredible complexity that can be found in molecular biology.
  • Biological Relevance: It is likely to have pharmaceutical applications, particularly in drug design. Compounds with such elaborate configurations can serve as starting points for creating novel therapeutics.
  • Protein Interaction: Its structure suggests potential for unique interactions with proteins and enzymes, which could pave the way for advancements in understanding metabolic pathways.
  • Research Implications: The analysis of such compounds can lead to deeper insights into molecular recognition, signaling pathways, and the development of biomimetic materials.
  • Synthetic Challenges: The synthesis of such a compound is not trivial and could involve multiple steps and strategies, making it a prime subject for studies in synthetic methodology.

This compound exemplifies how chemical structures not only define physical properties but also correlate closely with biological function. As a chemist, one might marvel at the creativity and precision needed to build such molecules and their importance in advancing medicinal chemistry and drug development.