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Berberine iodide

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Identification
Molecular formula
C40H44I2N2O6
CAS number
5956-60-5
IUPAC name
6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;diiodide
State
State

At room temperature, berberine iodide is a solid compound. It is stable under normal conditions and is commonly used in its solid form for various applications, particularly in research.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
208.00
Boiling point (Kelvin)
481.15
General information
Molecular weight
818.57g/mol
Molar mass
818.5650g/mol
Density
2.0800g/cm3
Appearence

Berberine iodide appears as a yellow to dark yellow crystalline powder. It is known for its intense yellow color, similar to other berberine salts, and can form needle-like crystals.

Comment on solubility

Solubility of 6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;diiodide

The solubility of the compound 6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;diiodide can be discussed in terms of its unique structural characteristics and ionic composition:

  • Polarity: As a quaternary ammonium compound, it is expected to possess significant polarity, which typically enhances solubility in polar solvents like water.
  • Ionic Interaction: The presence of iodide ions can facilitate solubility in aqueous solutions due to ion-dipole interactions.
  • Hydrogen Bonding: The compound may also form hydrogen bonds with water, further increasing its solubility.
  • Solvent Specificity: This compound may have high solubility in organic solvents due to its larger organic structure.

However, it is important to note that the exact solubility will depend on factors such as temperature, pH, and the presence of other solutes.

Overall, while the ionic nature suggests reasonable solubility in polar solvents, the complex organic structure indicates that polarity and solvent type will significantly influence solubility characteristics.

Interesting facts

Interesting Facts about 6-[4-(6,7-Dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium; Diiodide

This complex compound, characterized by its intricate structure and unique properties, presents a fascinating study for chemists and pharmacologists alike. Here are some interesting aspects of this molecule:

  • Structural Complexity: The compound features a dual isoquinolinium framework, which contributes to its *biological activity* and potential therapeutic applications.
  • Potential Applications: Compounds of this nature have shown promise in medicinal chemistry, particularly in developing *antimicrobial agents* and *antiviral drugs*.
  • Mechanism of Action: The isoquinolone moiety may interact with various biological pathways, making it an interesting candidate for *research in drug design* and *development*.
  • Absorption and Distribution: The presence of multiple methyl groups and dioxolo motifs suggests intriguing *pharmacokinetic properties*, which are essential for assessing the compound's efficacy and safety.
  • Structure-Activity Relationship: The relationship between the structure of this compound and its biological activity opens avenues for *novel synthetic strategies* that could enhance its therapeutic efficacy.

As researchers continue to explore this compound, it becomes increasingly clear that its rich chemical landscape is ripe for *investigation and innovation.* The potential implications of such compounds in the field of *medicinal chemistry* are vast, encouraging further examination and comprehensive studies.

Synonyms
20320-91-6
1,3-Dioxolo(4,5-g)isoquinolinium, 6,6'-tetramethylenebis(5,6,7,8-tetrahydro-6,7-dimethyl-, diiodide
6,6'-Tetramethylenebis(5,6,7,8-tetrahydro-6,7-dimethyl-1,3-dioxolo(4,5-g)isoquinolinium) 2I
RefChem:219046
DTXSID40942475
6,6'-(Butane-1,4-diyl)bis(6,7-dimethyl-5,6,7,8-tetrahydro-2H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium) diiodide