Berberine chloride | Solubility of Things

Identification

Molecular formula

C₂₀H₁₈NO₄⁺

CAS number

633-66-9

IUPAC name

6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium

State

At room temperature, berberine chloride is typically found in a solid crystalline state.

Melting point (Celsius)

196.00

Melting point (Kelvin)

469.15

Boiling point (Celsius)

542.00

Boiling point (Kelvin)

815.15

General information

Molecular weight

336.36g/mol

Molar mass

336.3610g/mol

Density

1.2600g/cm³

Appearence

Berberine chloride typically appears as a yellow crystalline powder. It is known for its bright yellow color, which has been historically used as a dye. It tends to form needle-like crystals when crystallized from water.

Comment on solubility

Solubility of 6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium

The solubility of complex organic compounds such as 6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium can present interesting challenges. Due to its intricate structure, solubility is influenced by several factors:

Polarity: The presence of dioxolo and isoquinoline structures can significantly affect the compound's polarity, impacting its solubility in polar solvents such as water.
Hydrophobic vs. Hydrophilic Characteristics: The dimethyl groups and butyl chains may introduce hydrophobic characteristics, making the compound less soluble in water but potentially more soluble in organic solvents like ethanol or chloroform.
Interactions: Intermolecular interactions, such as hydrogen bonding and π-π stacking, play a critical role in determining solubility.

In conclusion, while the solubility of this compound may be limited in aqueous environments, it could exhibit higher solubility in organic solvents. This intricate balance of characteristics requires careful consideration when predicting solubility behavior for practical applications.

Interesting facts

Exploring 6-[4-(6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-6-yl)butyl]-6,7-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium

This compound is a fascinating example of a complex molecular structure characterized by its unique rings and functional groups. Its intricate design makes it a subject of interest in both organic chemistry and pharmaceutical research.

Key Highlights

Structural Intricacies: The molecular backbone features a dioxoloisoquinoline moiety, which places it among a group of compounds known for their biological activities, such as antimicrobial and anticancer effects.
Dimethyl Substituents: The presence of dimethyl groups enhances its lipophilicity, potentially influencing its absorption and bioavailability in biological systems.
Potential Applications: Compounds of this nature could serve as lead compounds in drug discovery, especially in the realm of targeting complex diseases. Scientists often explore its analogs for enhanced therapeutic properties.
Research Interest: The study of such compounds is essential in understanding their interaction at the molecular level, paving the way for new treatments and advancements in medicinal chemistry.

As noted by many researchers, “Understanding the intricate details of such structures allows chemists to innovate and inspire new applications and solutions within the pharmaceutical industry.” This compound exemplifies how detailed structural features can provide insights into their potential mechanisms of action and efficacy.

Conclusion

In summary, this compound not only contributes to the vast field of chemical science but also showcases the potential for real-world applications that can significantly impact health and medicine. Its exploration could lead to better-designed drugs and a deeper understanding of their functionality.