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6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine

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Identification
Molecular formula
C14H15ClN2
CAS number
16800-65-2
IUPAC name
6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine
State
State

At room temperature, this compound is typically solid. It remains stable under normal environmental conditions, and due to its solid state, it is often handled in powdered or crystal form.

Melting point (Celsius)
145.52
Melting point (Kelvin)
418.67
Boiling point (Celsius)
340.45
Boiling point (Kelvin)
613.60
General information
Molecular weight
250.74g/mol
Molar mass
250.7390g/mol
Density
1.2003g/cm3
Appearence

This compound typically appears as a white crystalline solid. Its crystalline structure and purity can cause variations in form, ranging from powdery texture to more granular crystals. When impure, it may exhibit slight discoloration.

Comment on solubility

Solubility of 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine

The solubility of 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine can be intriguing, given its structural complexity. This compound exhibits unique characteristics that influence its solubility in various solvents.

Factors Affecting Solubility

Several factors can affect the solubility of this compound:

  • Molecular Structure: The presence of the 4-chlorophenyl group may enhance solubility in organic solvents while making it less soluble in polar solvents due to hydrophobic interactions.
  • Polarity: The non-polar parts of the molecule may limit its solubility in polar solvents, suggesting a possible preference for non-polar or weakly polar solvents.
  • Hydrogen Bonding: If the compound can form hydrogen bonds, this could enhance solubility in appropriate solvents.

Expected Solubility Characteristics

Consequently, you might observe:

  • Moderate Solubility: In organic solvents such as ethanol or acetone.
  • Poor Solubility: In water or highly polar solvents, consistent with similar compounds.

In conclusion, the solubility profile of 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine will largely depend on its molecular interactions influenced by the factors listed above. Understanding these characteristics is crucial in predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about 6-(4-Chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine

The compound 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine, often classified within the larger family of benzodiazepines, showcases some fascinating attributes that highlight its relevance in both medicinal chemistry and organic synthesis. Here are some intriguing facts:

  • Structure and Stability: The unique bicyclic structure of benzodiazocines contributes to their chemical stability and their ability to interact with specific biological targets.
  • Pharmacological Potential: Compounds of this class are frequently investigated for their potential sedative, anxiolytic, and muscle-relaxant properties, making them of high interest in the field of pharmacology.
  • Functional Groups: The presence of the 4-chlorophenyl group can significantly influence the compound's biological activity and potency. The chlorine substitution often enhances the lipophilicity of the molecule, which can lead to increased absorption in biological systems.
  • Synthetic Pathways: Chemical scientists often explore various synthetic pathways to create compounds like this, utilizing methods such as cyclization and functional group transformations. An understanding of reaction mechanisms is crucial in devising efficient synthesis routes.
  • Research Applications: Beyond pharmacology, this compound serves as an important lead structure for designing new drugs aimed at treating various conditions, including anxiety and seizures. Researchers are continually seeking to improve potency and reduce side effects.

As noted by one researcher, “The exploration of benzodiazepine derivatives has opened doors to numerous therapeutic avenues, allowing us to combat a range of psychological disorders.” The ongoing study of compounds like 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine embodies the intersection of chemical innovation and medical research.

Synonyms
1-(4-Chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine
13958-79-7
NSC 289757
NSC289757
NSC-289757
Oprea1_058190
CHEMBL132415
SCHEMBL11845495
6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine
1-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-[2,5]benzodiazocine