Skip to main content

Clonidine

ADVERTISEMENT
Identification
Molecular formula
C9H9Cl3N2
CAS number
4205-91-8
IUPAC name
6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine-2,5-diium;dichloride
State
State

Clonidine, as a chemical compound, is a solid at room temperature. It is usually processed in a hydrochloride salt form for medicinal use, which aids in its stability and oral absorption.

Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
266.56g/mol
Molar mass
266.5620g/mol
Density
1.2800g/cm3
Appearence

Clonidine, in its hydrochloride form, typically appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. Clonidine is used in pharmaceutical formulations, often forming part of tablets or extended-release tablets.

Comment on solubility

Solubility of 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine-2,5-diium;dichloride

The solubility of 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine-2,5-diium;dichloride can be influenced by several factors, particularly its ionic and aromatic characteristics. Understanding its solubility can help predict its behavior in various solvents.

Key Factors Influencing Solubility:

  • Polarity: The presence of ionic groups and polar bonds generally increases solubility in polar solvents like water.
  • Aromatic Systems: The benzodiazocine structure suggests a degree of hydrophobic character which may limit solubility in polar solvents.
  • Interactions: Salt forms, such as dichloride, show enhanced solubility in water due to ion-dipole interactions.

As a result, one might find that:

  • This compound is likely to exhibit good solubility in polar solvents like methanol and ethanol.
  • However, it may have lower solubility in non-polar solvents, such as hexane and toluene, due to its polar and ionic nature.
  • Solubility could vary based on temperature, pressure, and the specific solvent used.

In conclusion, while the compound's dual ionic nature suggests favorable solubility characteristics in water, the presence of its aromatic system may introduce complexities. Therefore, careful experimentation is recommended to fully characterize its solubility profile across different solvents.

Interesting facts

Interesting Facts about 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine-2,5-diium;dichloride

This intriguing compound features a unique combination of structural elements that contribute to its significance in chemical and pharmaceutical contexts. Here are some fascinating details:

  • Unique Structure: The compound showcases a benzodiazocine structure, indicating potential psychoactive effects, which are often studied in the realm of neurochemistry.
  • Chlorinated Phenyl Group: The presence of the 4-chlorophenyl substituent is noteworthy, as chlorinated aromatic compounds can exhibit varied biological activity, potentially enhancing efficacy in medicinal chemistry.
  • Ionization State: As a diium compound, it carries a positive charge from the nitrogen atoms, which may influence its solubility and interaction with biological targets.

This compound's potential applications may include:

  1. Pharmaceutical Uses: Due to its structural motifs, it may emerge as a candidate for developing new therapeutic agents suitable for treating a range of neurological disorders.
  2. Research Applications: Its unique properties make it a valuable subject for research into chemical reactivity and pharmacokinetics.
  3. Advanced Material Science: Given the complexity of its molecular structure, insights gained from studying this compound could further the development of advanced materials or organometallic systems.

In summary, 6-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine-2,5-diium;dichloride represents a fascinating intersection of organic chemistry and pharmacology. As research continues to unveil its potential applications and properties, it remains a compound of interest for scientists and students alike.

Synonyms
WY 5244
2,5-BENZODIAZOCINE, 1-(p-CHLOROPHENYL)-1,2,3,4,5,6-HEXAHYDRO-, DIHYDROCHLORIDE
1-(p-Chlorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine dihydrochloride
2,5-Benzodiazocine, 1-(4-chlorophenyl)-1,2,3,4,5,6-hexahydro-, dihydrochloride
13822-05-4
576L22D18T
UNII-576L22D18T