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Olanzapine

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Identification
Molecular formula
C17H20N4S
CAS number
132539-06-1
IUPAC name
6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one
State
State

At room temperature, Olanzapine is in a solid state. It's typically processed into tablet form for pharmaceutical use.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.20
Boiling point (Celsius)
565.50
Boiling point (Kelvin)
838.70
General information
Molecular weight
312.44g/mol
Molar mass
312.4390g/mol
Density
1.2457g/cm3
Appearence

Olanzapine is a pale yellow or yellow crystalline solid. It can sometimes appear off-white, depending on specific manufacturing methods or impurities present in small quantities.

Comment on solubility

Solubility of 6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one

The solubility of 6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one can be influenced by several factors, including its molecular structure and the presence of functional groups.

Key Points Affecting Solubility:

  • Polarity: The compound contains a piperazine moiety, which is polar and can interact with polar solvents like water. However, the benzothiepin structure may add hydrophobic characteristics.
  • Solvent Choice: It is likely to exhibit higher solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) compared to water.
  • Temperature: Increased temperature may enhance solubility, as many organic compounds dissolve better in warm solvents.

While detailed solubility data may not be readily available for this specific compound, it is important to consider the overall balance of polar and non-polar characteristics. Laboratory testing can provide precise insights on solubility profiles and suitability in various applications.
Overall, the combination of its benzothiepin core and piperazine side chain suggests a nuanced solubility behavior that warrants further investigation.

Interesting facts

Interesting Facts About 6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one

6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one is a fascinating compound that belongs to the class of benzothiepins, known for their unique molecular structure and medicinal properties. Here are a few engaging aspects of this compound:

  • Pharmacological Potential: This compound is under investigation for its potential use in treating various neurological disorders. Its intricate structure allows it to interact with specific receptors in the brain, opening avenues for novel therapeutic approaches.
  • Molecular Diversity: The inclusion of a piperazine moiety contributes to the compound's molecular diversity, which can lead to enhanced bioactivity. Piperazines are prominent in many pharmaceutical applications due to their ability to modulate neurotransmitter systems.
  • Structure-Activity Relationship (SAR): Understanding the relationship between its chemical structure and biological activity is crucial. Scientists study these effects to optimize the design of new compounds with improved efficacy and safety profiles.
  • Synthetic Challenges: The synthesis of this compound involves several steps, requiring a strong grasp of organic chemistry techniques. Each synthetic route can lead to variances in yield and purity, making it a compelling subject for chemists and students alike.
  • Research Opportunities: As new studies emerge, there are growing opportunities for research into its mechanism of action, making it a rich topic for graduate research projects and pharmaceutical studies.

Overall, 6-(4-methylpiperazin-1-yl)-6H-benzo[b][1]benzothiepin-5-one exemplifies the complexities and potential of synthetic organic compounds in medicinal chemistry. As scientists continue to explore its properties, we may uncover breakthroughs that could significantly impact healthcare.

Synonyms
AKOS005065433