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6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine

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Identification
Molecular formula
C18H19N3S
CAS number
39011-93-5
IUPAC name
6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
State
State

Under standard conditions, 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine is a solid. Its crystalline nature makes it stable under normal atmospheric conditions, and it is usually stored in a dry, sealed container to maintain its integrity and prevent degradation.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.00
Boiling point (Celsius)
559.20
Boiling point (Kelvin)
832.20
General information
Molecular weight
305.44g/mol
Molar mass
305.4140g/mol
Density
1.3100g/cm3
Appearence

It is typically a crystalline solid, often appearing as a white to off-white powder or crystals. This compound may sometimes also be available in a slightly colored form depending on purity and the presence of impurities. It is generally handled in powdered form in laboratory settings.

Comment on solubility

Solubility of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine

Understanding the solubility of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine is crucial for its potential applications in pharmacology and material science. The solubility characteristics of this compound are influenced by various factors:

  • Polarity: This compound contains both hydrophilic (piperazine group) and hydrophobic (benzothiazepine framework) regions, suggesting that it may exhibit moderate solubility in polar solvents.
  • pH Dependency: Its solubility may vary significantly with changes in pH, as the protonation of the piperazine nitrogen can enhance aqueous solubility.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature; this is especially pertinent in application contexts where temperature control is feasible.

It is often noted that:

"The solubility of a compound is not just a binary state; it is a dynamic property influenced by environmental conditions."

This underscores the importance of conducting experiments under varied conditions to fully understand the solubility profile of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine. Careful consideration of solvent choice and conditions will yield the best results in solubility studies.

Interesting facts

Interesting Facts About 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine

6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine is a fascinating compound that belongs to a class of chemicals known for their versatile applications in medicinal chemistry. Here are some intriguing points to consider:

  • Pharmacological Potential: This compound is often investigated for its potential therapeutic uses, particularly in the treatment of neurological and psychiatric disorders. Its unique structure allows it to interact with various neurotransmitter systems, which makes it a subject of interest in drug development.
  • Complex Structure: The name itself hints at the compound's intricate structure, which features both a benzothiazepine core and a piperazine moiety. Such complexity can lead to a variety of chemical properties and reactions, making it an interesting subject for organic synthesis.
  • Structure-Activity Relationship (SAR): Researchers frequently engage in SAR studies to determine how modifications to the structure, such as changes to the piperazine group, can enhance the biological activity or selectivity of the compound. This can lead to the discovery of more effective medications with fewer side effects.

The study of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine exemplifies the intersection of chemistry and pharmacology, showcasing how structural nuances can significantly impact the therapeutic potential of compounds. As you delve deeper into the world of medicinal chemistry, the exploration of such compounds highlights the importance of both chemical structure and biological function in drug design.

In conclusion, while 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine may not yet be a household name, its study could lead to promising advancements in therapeutics and a better understanding of complex chemical interactions.

Synonyms
1977-09-9
DIBENZO(b,f)(1,4)THIAZEPINE, 11-(4-METHYL-1-PIPERAZINYL)-
BRN 0931391
11-(4-Methyl-1-piperazinyl)benzo(b,f)(1,4)thiazepine
DTXSID00173465
Dibenzo[b,f][1,4]thiazepine, 11-(4-methyl-1-piperazinyl)-
DTXCID6095956
11-(4-Methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine
6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
Quetiapine Impurity 8
11-(4-Methyl-1-piperazinyl)dibenzo[b,f][1,4]thiazepine
FBT3XHQ9TS
SCHEMBL144624
CHEMBL127025
FD182392