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6-(4-Methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

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Identification
Molecular formula
C19H21N3O
CAS number
58218-92-5
IUPAC name
6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
State
State

This compound is a solid at room temperature.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.10
Boiling point (Celsius)
398.30
Boiling point (Kelvin)
671.50
General information
Molecular weight
305.40g/mol
Molar mass
305.3520g/mol
Density
1.2310g/cm3
Appearence

6-(4-Methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine typically appears as a crystalline powder. The compound might be off-white to light beige in color and is characterized by its solid form at room temperature. This compound does not have a distinctive odor.

Comment on solubility

Solubility of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

The solubility of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine in various solvents is an important factor for its application in medicinal chemistry. Here are some key points about its solubility:

  • Polar vs Non-Polar Solvents: This compound is expected to have higher solubility in polar solvents due to the presence of the piperazine group, which can interact favorably with polar molecules.
  • Aqueous Solubility: It may have limited solubility in water; however, the piperazine moiety could enhance its interactions with water, depending on the pH of the environment.
  • Solvent Versatility: Generally, it may dissolve well in organic solvents such as ethanol and DMSO, which can help in various biological assays.
  • Concentration Dependency: The solubility could vary with concentration, indicating that at higher concentrations, precipitation might occur, necessitating careful handling in solutions.

In conclusion, understanding the solubility profile of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine is critical for its formulation in pharmaceutical applications. The intricate balance between its chemical structure and solvent properties significantly influences its bioavailability and efficacy in therapeutic settings.

Interesting facts

Exciting Insights into 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, often recognized in the context of medicinal chemistry, is a fascinating compound that holds potential therapeutic applications. Here are some intriguing facts about this compound:

  • Structural Significance: The structure features a unique benzoxazepine core, integrating both benzene and oxazepine rings. This fusion grants it interesting electronic properties that are pivotal in drug design.
  • Pharmacological Potential: Due to its piperazine moiety, this compound has been explored for its role in the treatment of various neurological conditions, particularly in the realm of antidepressant and antipsychotic medications.
  • Diverse Derivatives: Researchers have synthesized numerous derivatives of this compound, allowing for the exploration of a wide array of biological activities. Some modifications aim to enhance efficacy while reducing side effects.
  • Research Focus: Many studies have focused on its ability to interact with specific neurotransmitter receptors, contributing to our understanding of the central nervous system and its disorders.

As scientists delve deeper into the characteristics and mechanisms of 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine, the potential for discovering new treatments and understanding complex biological systems grows. This compound not only underscores the importance of chemical structure in determining pharmacological activity but also highlights the synergy between chemistry and medicine.

In the words of a prominent chemist, "Chemistry is the science of connections, and compounds like this one are fascinating junctions in our quest for innovation."

Synonyms
DIBENZ(b,f)(1,4)OXAZEPINE, 11-(4-METHYL-1-PIPERAZINYL)-
BRN 0563562
11-(4-Methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine
DTXSID50174588
11-(4-Methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine
Dibenz[b,f][1,4]oxazepine, 11-(4-methyl-1-piperazinyl)-
DTXCID6097079
2058-53-9
6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
11-(4-Methylpiperazino)dibenzo[b,f][1,4]oxazepine
SCHEMBL140907
CHEMBL339414
NL9E88U79L
AKOS040751211