Deferoxamine | Solubility of Things

Identification

Molecular formula

C₂₅H₄₈N₆O₈

CAS number

70-51-9

IUPAC name

6-[6-(1-methoxyindol-3-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid

State

At room temperature, deferoxamine is typically in a solid state, often as a fine powder.

Melting point (Celsius)

150.00

Melting point (Kelvin)

423.00

Boiling point (Celsius)

760.00

Boiling point (Kelvin)

1 033.00

General information

Molecular weight

560.70g/mol

Molar mass

560.6950g/mol

Density

0.7268g/cm³

Appearence

Deferoxamine is typically found as a white to off-white, amorphous or crystalline powder. This compound may also appear as a lyophilized powder when prepared for medical use.

Comment on solubility

Solubility Characteristics

The compound 6-[6-(1-methoxyindol-3-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid (C₂₅H₄₈N₆O₈) presents an intriguing profile in terms of solubility. Understanding solubility is essential for its applications as it affects bioavailability, therapeutic efficacy, and formulation development. Here are some key aspects to consider:

Polarity: The presence of multiple functional groups, including hydroxamic acid, suggests that this compound may exhibit polar characteristics that influence its solubility in solvents.
Hydrogen Bonding: The hydroxamic acid moiety can engage in hydrogen bonding, enhancing solubility in polar solvents such as water.
Solvent Diversity: It may show differing solubility in various solvents. For example, it could be more soluble in dimethyl sulfoxide (DMSO) or methanol compared to non-polar solvents.
pH Dependence: The solubility can also be pH-dependent, particularly for acid and base functionalities that may ionize, thus affecting solubility under different conditions.
Crystalline vs. Amorphous: Depending on its crystalline structure, solubility can vary significantly; amorphous forms often have higher solubility compared to their crystalline counterparts.

As stated, "the solubility of a compound is key to unlocking its potential." Therefore, evaluating the solubility of this particular compound is crucial for its practical applications in various scientific fields.

Interesting facts

Interesting Facts about 6-[6-(1-methoxyindol-3-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid

The compound 6-[6-(1-methoxyindol-3-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid is a fascinating example of complex organic chemistry. This molecule features a unique structure that integrates both indole and hydroxamic acid functionalities, offering intriguing properties that make it a subject of interest in medicinal chemistry.

Key Features:

Multi-Functional Moiety: The incorporation of the hydroxamic acid group may contribute to biological activity, specifically in enzyme inhibition and drug design.
Potential for Therapeutic Use: Molecules containing indoles are often associated with a variety of biological activities, including anti-cancer properties, making this compound a potential candidate for further pharmaceutical exploration.
Complex Structure: Its bicyclic tetrazole framework along with multiple keto groups suggests that this compound could exhibit interesting chemical reactivity and stability.

It’s remarkable to note that the chemistry of such complex compounds can lead to significant advancements in drug development. The fusion of different chemical entities, as seen in this compound, highlights the innovative approaches chemists take in creating potential pharmacophores.

"Each compound tells a story, and this one whispers of possibilities yet to be explored."

In conclusion, the study of 6-[6-(1-methoxyindol-3-yl)-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecan-9-yl]hexanehydroxamic acid opens doors to understanding complex organic molecules that may play an essential role in future therapeutic applications.