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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[6-[6-[[4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate
State
State

At room temperature, erythromycin is typically in solid form as a crystalline powder. It is stable under standard conditions and does not spontaneously decompose or evaporate in air.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
107.00
Boiling point (Kelvin)
380.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2400g/cm3
Appearence

Erythromycin is a white to slightly yellow, odorless, crystalline powder. It can occur in different forms, such as anhydrous form or hydrated forms, which may affect the shade of white in its appearance.

Comment on solubility

Solubility of C37H67NO13

The solubility of the compound 6-[6-[[4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate presents a complex scenario due to its intricate molecular structure and considerable size.

In general, the solubility of organic compounds like this one can be influenced by various factors:

  • Molecular Size: Larger molecules often exhibit reduced solubility in polar solvents owing to their extensive hydrophobic regions.
  • Functional Groups: The presence of hydroxyl (-OH) and dimethylamino groups can enhance solubility in polar solvents like water by promoting hydrogen bonding.
  • Polarity: The balance between hydrophilic (water-attracting) and hydrophobic (water-repelling) regions in the molecule significantly affects its overall solubility characteristics.
  • Temperature: Typically, an increase in temperature can lead to enhanced solubility for many compounds, making it an essential condition to consider in solubility studies.

It's important to note that, while some segments of the molecule may interact favorably with polar solvents, the large hydrophobic portions might impede overall solubility, leading to limited dissolution in aqueous environments. As a result, one might summarize the solubility of this compound as moderate to low in water but potentially more soluble in organic solvents, depending on specific conditions.

Interesting facts

Interesting Facts About 6-[6-[[4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate

This compound, with its impressively complex structure, showcases the fascinating world of organic chemistry and its intricate molecular architecture. Here are some interesting insights:

  • Diverse Applications: Due to its unique functional groups, this compound may exhibit a range of biological activities. Compounds of similar structure have been investigated for medicinal uses, particularly in the development of drugs targeting specific diseases.
  • Structural Complexity: The presence of multiple hydroxy and methoxy groups indicates potential for hydrogen bonding, which often enhances solubility in biological membranes. This complexity is a hallmark of many natural products derived from plants.
  • Synthetic Pathways: The synthesis of such multi-functional compounds involves intricate reactions, including alkylation, hydroxylation, and esterification. This highlights the creativity and problem-solving required in organic synthesis.
  • Potential as Bioactive Molecule: Similar molecules have displayed antioxidant properties or have been linked to cancer prevention. This underlines the importance of chemical diversity in exploring new therapeutic agents.
  • Natural Product Inspiration: Many complex compounds are derived from natural sources, where plants and microorganisms often produce intricate chemicals for defense and competition. Understanding these compounds contributes to the field of drug discovery.

In essence, this compound is a prime example of how organic chemistry merges with biology, offering a glimpse into the potential for new discoveries through the study of structural intricacies. The exploration of such compounds not only advances our understanding of chemistry but also opens up pathways for novel therapeutic developments.

Synonyms
6-[(6-{[4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl)oxy]-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate