6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one

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Identification

Molecular formula
C16H13FN3O
CAS Number
870281-82-6
IUPAC Name
6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one
Molecular Weight
282.31g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3295g/cm3
Synonyms
afloqualone
Interesting facts

Exploring 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one

6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one is a fascinating compound within the realm of medicinal chemistry, primarily recognized for its diverse bioactive properties. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: The compound exhibits a promising profile in drug discovery, specifically in the development of therapeutics targeting various diseases, including cancers and neurodegenerative disorders.
  • Structural Characteristics: The unique fluoromethyl group contributes to its chemical reactivity and lipophilicity, enhancing its ability to penetrate biological membranes.
  • Quinazoline Core: The quinazoline moiety is known for its biological significance, being a scaffolding structure for numerous pharmacologically active compounds. The fused ring system provides stability, making it an excellent candidate for drug development.
  • Amino Functionality: The amino group in the 6-position is pivotal for interactions with biological targets, often facilitating hydrogen bonding, which is critical in receptor binding and activity.
  • O-tolyl Substitution: The presence of the o-tolyl ring can modulate the compound's overall activity and selectivity, potentially paving the way for selective targeting of specific receptors.

In summary, 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one is not just another chemical compound; its strategic functional groups and structural composition make it an exciting subject for ongoing research. As scientists delve deeper into understanding and harnessing its properties, we can expect it to play a significant role in the future of therapeutic developments.

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