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6-Amino-3-(4-aminophenyl)-1,3-benzoxazine-2,4-dione

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Identification
Molecular formula
C14H11N3O2
CAS number
71675-87-1
IUPAC name
6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one
State
State

This compound is generally solid at room temperature. It forms crystals that are stable under normal environmental conditions.

Melting point (Celsius)
265.00
Melting point (Kelvin)
538.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
253.26g/mol
Molar mass
253.2500g/mol
Density
1.4550g/cm3
Appearence

The compound typically appears as a pale yellow crystalline powder. Its appearance may vary slightly depending on purity and specific form, but it is generally opaque and has a consistent texture.

Comment on solubility

Solubility of 6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one

The solubility of 6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one is influenced by several factors, including its polar and non-polar characteristics. Here are some key points to consider:

  • Polarity: The presence of amino groups in the structure enhances the overall polarity of the compound, which can promote solubility in polar solvents such as water.
  • Solvent Interaction: It is particularly soluble in solvents that can engage in hydrogen bonding, making polar protic solvents like alcohols and amines potential candidates for effective dissolution.
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature. Therefore, the solubility profile may improve when the compound is heated.
  • pH Influence: The solubility is also likely to vary with pH due to the ionization of amino groups, enabling the compound to become more soluble in acidic or basic environments.

In summary, the solubility of 6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one is primarily affected by its structural characteristics and external conditions such as solvent polarity, temperature, and pH. Understanding these factors is crucial for practical applications in fields such as pharmaceuticals where solubility is a key parameter.

Interesting facts

Interesting Facts about 6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one

6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one is a fascinating compound that has garnered significant attention in the field of medicinal chemistry. This compound is a member of the benzoxazine class, known for its interesting structural features and biological activities.

Key Features:

  • Versatile Molecular Structure: The compound features an amino group, which enhances its reactivity and potential as a therapeutic agent.
  • Biological Activity: Research has shown that compounds with the benzoxazine core often exhibit:
    • Antioxidant properties
    • Anticancer activities
    • Anti-inflammatory effects
  • Synthetic Venues: It can be synthesized through a variety of methods, including condensation reactions, making it accessible for further study.
  • Pharmaceutical Applications: The ability to modify its structure opens avenues for developing novel drugs targeting various diseases.

Historically, benzoxazine derivatives have been noted for their importance in synthetic organic chemistry and their role in materials science due to their polymerization properties. This particular compound illustrates the intersection of organic synthesis and pharmacology, evolving into a promising candidate for drug discovery.

As stated by researchers in the field, "The unique combination of structural attributes makes 6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one a vital compound for future therapeutic development." This sentiment underscores the significance of continuing to explore its potential applications.

In summary, this compound exemplifies the rich potential within organic compounds to serve crucial roles in health sciences, paving the way for innovative treatments and methodologies.

Synonyms
18672-13-4
BRN 1588945
4H-1,3-BENZOXAZIN-4-ONE, 6-AMINO-3-(p-AMINOPHENYL)-2,3-DIHYDRO-
6-Amino-3-(p-aminophenyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one
DTXSID50171936
DTXCID2094427
6-amino-3-(4-aminophenyl)-2H-1,3-benzoxazin-4-one