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Coumarin 6

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Identification
Molecular formula
C14H10N2O2
CAS number
38215-99-5
IUPAC name
6-amino-3-(4-pyridyl)chromen-2-one
State
State

At room temperature, 6-amino-3-(4-pyridyl)chromen-2-one is typically found in a solid state.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
262.28g/mol
Molar mass
262.2800g/mol
Density
1.3540g/cm3
Appearence

6-amino-3-(4-pyridyl)chromen-2-one is a crystalline solid with a pale yellow to yellow appearance. It might display slight fluorescence under UV light due to its conjugated structure.

Comment on solubility

Solubility of 6-Amino-3-(4-pyridyl)chromen-2-one

The solubility of 6-amino-3-(4-pyridyl)chromen-2-one can be characterized by various factors that influence its behavior in different solvents. This compound, featuring both amino and pyridyl functional groups, demonstrates notable solubility characteristics that can be summarized as follows:

  • Polar Solvents: The presence of the amino group typically enhances solubility in polar solvents, such as water and alcohols, due to the ability to form hydrogen bonds.
  • Non-Polar Solvents: Conversely, solubility in non-polar solvents may be limited. Compounds like this one tend to favor polar environments because of their functional groups.
  • pH Sensitivity: Solubility can be significantly affected by pH levels. In acidic conditions, the amino group can be protonated, potentially increasing solubility.

As a general observation, it is often stated that:

"The more polar a compound, the more soluble it is in polar solvents."

This principle applies well to 6-amino-3-(4-pyridyl)chromen-2-one, where its polar characteristics influence its solubility profile. Understanding these interactions is crucial when considering applications in pharmaceuticals, where solubility affects bioavailability and therapeutic efficacy.

Interesting facts

Interesting Facts about 6-amino-3-(4-pyridyl)chromen-2-one

6-amino-3-(4-pyridyl)chromen-2-one, often associated with pharmacological research, is an intriguing compound that showcases the fascinating intersection of chemistry and biology. Here are some compelling insights:

  • Versatile Structure: This compound features a chromenone backbone, which is known for its ability to participate in various chemical reactions. The presence of the amino and pyridine functional groups contributes to its rich chemical reactivity.
  • Pharmacological Potential: Research shows that derivatives of the chromenone framework have exhibited potential biological activities, including anti-inflammatory, antioxidant, and even anticancer properties. This positions 6-amino-3-(4-pyridyl)chromen-2-one as a candidate for further study in medicinal chemistry.
  • Receptor Interactions: Its structural features suggest potential interactions with various biological receptors, making it an interesting subject for drug design aimed at targeting specific pathways in diseases.
  • Synergistic Effects: The combination of the amino group and the pyridine ring can enhance the activity of this compound in biological systems, often resulting in synergistic effects that improve therapeutic outcomes.
  • Historical Context: Chromenones have been studied for decades, but the exploration of specific derivatives like 6-amino-3-(4-pyridyl)chromen-2-one is relatively new, indicating a growing interest in synthesizing and evaluating novel derivatives to expand their potential applications.

As research in this area continues to evolve, the implications of studying compounds like 6-amino-3-(4-pyridyl)chromen-2-one remain profound, influencing the development of new therapeutic agents and enhancing our understanding of bioactive molecules.

Synonyms
3390-71-4
6-Amino-3-(4-pyridyl)coumarin
BRN 1077371
COUMARIN, 6-AMINO-3-(4-PYRIDYL)-
DTXSID20187524
DTXCID80110015
6-Amino-3-(pyridin-4-yl)-2H-chromen-2-one
6-amino-3-pyridin-4-ylchromen-2-one