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6-Amino-3-(piperidine-1-carbonyl)chromen-2-one

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Identification
Molecular formula
C15H16N2O3
CAS number
.
IUPAC name
6-amino-3-(piperidine-1-carbonyl)chromen-2-one
State
State
At room temperature, 6-Amino-3-(piperidine-1-carbonyl)chromen-2-one is a solid. It is typically stable under normal conditions of temperature and pressure.
Melting point (Celsius)
215.00
Melting point (Kelvin)
488.20
Boiling point (Celsius)
435.10
Boiling point (Kelvin)
708.30
General information
Molecular weight
270.31g/mol
Molar mass
270.3080g/mol
Density
1.3490g/cm3
Appearence
6-Amino-3-(piperidine-1-carbonyl)chromen-2-one appears as an off-white to pale yellow crystalline solid. It may vary slightly in color due to the presence of impurities or structural differences in preparation.
Comment on solubility

Solubility of 6-amino-3-(piperidine-1-carbonyl)chromen-2-one

The solubility of 6-amino-3-(piperidine-1-carbonyl)chromen-2-one can be influenced by various factors, given its complex structure. Here are some key considerations regarding its solubility:

  • Polar Groups: The presence of amino and carbonyl functional groups may enhance the solubility in polar solvents, such as water and methanol.
  • Non-Polar Characteristics: The chromen-2-one backbone may impart some non-polar characteristics, potentially limiting its solubility in highly polar environments.
  • Solvent Compatibility: This compound might show better solubility in organic solvents like DMSO or DMF compared to aqueous solutions.
  • pH Dependency: Solubility could be affected by pH, especially due to the presence of the amino group, which can be protonated in acidic conditions, potentially increasing solubility.

In conclusion, while the solubility of 6-amino-3-(piperidine-1-carbonyl)chromen-2-one is likely variable, it is vital to assess it experimentally across a range of solvents to establish effective use in laboratory and pharmaceutical settings. As with many chemical compounds, a *thorough understanding of its solubility profile* will facilitate its applications in various fields.

Interesting facts

Interesting Facts about 6-Amino-3-(piperidine-1-carbonyl)chromen-2-one

6-Amino-3-(piperidine-1-carbonyl)chromen-2-one is an intriguing compound that has garnered attention in the realm of medicinal chemistry. Here are some interesting aspects of this compound:

  • Chemical Structure: This compound features a chromene backbone, which is a staple in many bioactive molecules. Chromenes are known for their role in various natural products and contribute to biological activity.
  • Biological Significance: The presence of the amino group in the 6-position enhances the pharmacological potential of this compound. Amino derivatives often participate in hydrogen bonding, which can improve interactions with biological targets.
  • Piperidine Linkage: The piperidine-1-carbonyl moiety adds another layer of complexity. Piperidine rings are commonly found in many pharmaceuticals, contributing to the compound’s ability to modulate biological processes.
  • Potential Applications: Compounds like 6-amino-3-(piperidine-1-carbonyl)chromen-2-one are often investigated for their potential as antimicrobial, anti-inflammatory, and anticancer agents. The diverse functionalities derived from its structure make it a candidate worth exploring in drug discovery.
  • Research Avenues: Ongoing research may focus on the synthesis of analogs to optimize potency and selectivity. Exploring the mechanism of action through computational modeling can also unveil its interactions at the molecular level.

In conclusion, the uniqueness of 6-amino-3-(piperidine-1-carbonyl)chromen-2-one lies in its distinctive molecular architecture, which offers a promising foundation for the development of novel therapeutics. As advances in the field continue, this compound stands as a testament to the creativity intrinsic to chemical science and the potential for discovery in medicinal applications.

Synonyms
18144-56-4
COUMARIN, 6-AMINO-3-(PIPERIDINOCARBONYL)-
6-Amino-3-(piperidinocarbonyl)coumarin
BRN 1259868
DTXSID90171152
5-20-03-00447 (Beilstein Handbook Reference)
DTXCID4093643
6-amino-3-(piperidine-1-carbonyl)chromen-2-one
6-Amino-3-(piperidine-1-carbonyl)-2H-chromen-2-one
6-AMINO-3-(PIPERIDIN-1-YLCARBONYL)COUMARIN