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Pyrimido[4,5-d]pyrimidine

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Identification
Molecular formula
C10H10N4O
CAS number
19600-35-8
IUPAC name
6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one
State
State
Solid at room temperature, characterized by its crystalline structure.
Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
526.00
Boiling point (Kelvin)
799.15
General information
Molecular weight
214.23g/mol
Molar mass
214.2340g/mol
Density
1.3145g/cm3
Appearence

White to light yellow crystalline powder.

Comment on solubility

Solubility of 6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one

The solubility of 6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one can be characterized by several key points:

  • Water Solubility: This compound exhibits moderate to low solubility in water, which can be influenced by the presence of amino groups that may form hydrogen bonds.
  • Solvent Dependence: Its solubility is likely to be affected by different solvents, with polar solvents generally promoting better dissolution compared to non-polar solvents.
  • pH Influence: The pH of the solution plays a critical role, as the amino groups can be protonated or deprotonated, altering its overall solubility characteristics.
  • Temperature Variation: An increase in temperature typically enhances solubility; however, the specific trend can vary, thus requiring careful examination.

In summary, the solubility of 6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one is governed by a complex interplay of molecular interactions and environmental factors, highlighting the importance of solvent choice and condition management for achieving optimal dissolution.

Interesting facts

Exploring 6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one

6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one is a fascinating compound with significant implications in the field of medicinal chemistry. Here are some intriguing facts that highlight its importance:

  • Pharmaceutical Applications: This compound is often investigated for its potential role as a therapeutic agent, particularly in the development of anti-cancer and anti-inflammatory medications. Its structure allows for interactions with various biological targets.
  • Biological Activity: The presence of amino groups in its structure is crucial for its activity. Amino groups are known to enhance solubility and can participate in hydrogen bonding, making compounds more effective in biological systems.
  • Structure-Activity Relationship (SAR): Researchers often study compounds like this one to understand how small changes in structure can lead to significant alterations in activity. The position of the amino groups can heavily influence the compound's behavior and effectiveness.
  • Metabolic Pathways: The metabolism of this compound is not only important for its pharmacokinetics but also plays a role in its detoxification and excretion processes in the body, which are vital for its therapeutic use.
  • Analytical Techniques: Studying this compound involves various analytical techniques such as NMR (Nuclear Magnetic Resonance) and HPLC (High-Performance Liquid Chromatography), which help in understanding its properties and behavior in different environments.

As we explore the intricate details of 6-amino-5-(4-aminophenyl)-1H-pyrimidin-2-one, we are reminded of the complex dance between chemical structure and biological function. Understanding these connections is key to unlocking new medications and treatments for a variety of conditions.

Synonyms
Amifenosine
Amiphenosine
Amifenozin
VUFB914
CYTOSINE, 5-(p-AMINOPHENYL)-
4650-29-7
5-(p-Aminophenyl)cytosine
5-(4-Aminophenyl)cytosine
4-Amino-5-(4-aminophenyl)-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 4-amino-5-(4-aminophenyl)-
DTXSID50196861
DTXCID90119352
2(1H)-Pyrimidinone, 4-amino-5-(4-aminophenyl)-(9CI)
AKOS024322427
DB-428404
6-Amino-5-(4-aminophenyl)-2(1H)-pyrimidinone