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Acriflavine

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Identification
Molecular formula
C13H15N2·H2SO4
CAS number
8063-24-9
IUPAC name
(6-aminoacridin-3-yl)ammonium;sulfate
State
State

At room temperature, acriflavine is typically a solid. It is not very volatile, and when handled, it should be done so in the solid state, usually as a powder or crystalline substance.

Melting point (Celsius)
247.00
Melting point (Kelvin)
520.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
286.33g/mol
Molar mass
286.3300g/mol
Density
1.3900g/cm3
Appearence

Acriflavine appears as an orange to reddish-brown powder or crystalline solid. It is known for its distinctive color, which can sometimes exhibit a greenish hue under certain lighting conditions. The compound can form a clear yellow or orange solution when dissolved in water.

Comment on solubility

Solubility of (6-aminoacridin-3-yl)ammonium sulfate

The solubility characteristics of (6-aminoacridin-3-yl)ammonium sulfate are quite intriguing, primarily influenced by its ionic nature and molecular structure. This compound typically exhibits variable solubility in different solvents, which can be summarized as follows:

  • Water: Generally, (6-aminoacridin-3-yl)ammonium sulfate is soluble in water due to the presence of the sulfate group, which significantly enhances its ability to dissolve due to ion-dipole interactions.
  • Organic Solvents: Solubility in organic solvents like ethanol or acetone is typically lower, as the polar ammonium and sulfate groups do not interact favorably with nonpolar molecules.
  • Temperature Influence: Like many ionic compounds, solubility often increases with temperature, making it more soluble in hot water than in cold.

It is essential to note that factors such as pH, presence of other ions, and specific concentrations can dramatically affect solubility. In essence, while (6-aminoacridin-3-yl)ammonium sulfate shows a good degree of solubility in water, its behavior in various media can vary; thus, understanding its solubility is key for its practical applications.

Interesting facts

Interesting Facts about (6-aminoacridin-3-yl)ammonium sulfate

(6-aminoacridin-3-yl)ammonium sulfate is a fascinating compound that bridges the fields of organic chemistry and biochemistry. Known for its unique structure and properties, this compound has attracted attention for various applications, particularly in medicinal chemistry and molecular biology.

Key Properties and Applications

  • Pharmacological Potential: This compound has been studied for its ability to interact with biological systems. Its acridine structure is characteristic of several compounds known for anticancer activity.
  • Fluorescent Properties: The acridine moiety often exhibits fluorescent characteristics, making it useful in imaging techniques and as a probe in bioluminescence studies.
  • DNA Interaction: Similar to other acridine derivatives, (6-aminoacridin-3-yl)ammonium sulfate can intercalate within DNA structures, potentially affecting replication and transcription processes.
  • Versatile Functionality: The amino group present in the structure enables further chemical modifications, enhancing its reactivity and allowing researchers to tailor its properties for specific applications.

Important Considerations

While (6-aminoacridin-3-yl)ammonium sulfate shows great promise, several important points should be noted:

  • Potential toxicity in certain concentrations requires careful handling and rigorous testing during experiments.
  • Its interactions with biological systems necessitate thorough studies to understand mechanisms of action and side effects.

In summary, (6-aminoacridin-3-yl)ammonium sulfate illustrates the intersection of chemistry and biology, opening pathways for innovative studies and applications in science. As research progresses, this compound could play a significant role in advancing therapeutic strategies and molecular diagnostics.