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N-Hydroxynaphthalene-1,8-imide

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Identification
Molecular formula
C13H8N2O2
CAS number
54937-86-9
IUPAC name
6-aminobenzo[de]isoquinoline-1,3-dione
State
State

At room temperature, this compound is typically a crystalline solid. Its physical nature makes it easy to handle in laboratory settings, and it usually remains stable under standard conditions.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
210.21g/mol
Molar mass
210.2050g/mol
Density
1.3400g/cm3
Appearence

6-Aminobenzo[de]isoquinoline-1,3-dione appears as a solid powder, typically white to off-white in color. Its crystalline structure can vary, but it generally forms fine particles, making it similar in appearance to fine table salt or sugar.

Comment on solubility

Solubility of 6-aminobenzo[de]isoquinoline-1,3-dione (C13H8N2O2)

The solubility of 6-aminobenzo[de]isoquinoline-1,3-dione is a crucial aspect that affects its applications in various fields, including pharmaceuticals and materials science. This compound exhibits interesting solubility characteristics due to its structural features.

Factors Influencing Solubility

Several factors can influence the solubility of this compound:

  • Polarity: The presence of polar functional groups in the molecule can enhance solubility in polar solvents, such as water.
  • Molecular Structure: The isoquinoline ring system and the amino group can affect intermolecular interactions, potentially enhancing solubility in organic solvents.
  • pH Sensitivity: The solubility can vary with pH, as protonation or deprotonation of the amino group may influence its ability to dissolve in aqueous media.

Conclusion

In summary, the solubility of 6-aminobenzo[de]isoquinoline-1,3-dione is influenced by its molecular structure and intermolecular interactions. It is essential to consider these factors when exploring its uses and formulations in various chemical applications. While specific solubility data may be limited, understanding these underlying principles allows for better predictions and practical uses of the compound.

Interesting facts

Interesting Facts about 6-Aminobenzo[de]isoquinoline-1,3-dione

6-Aminobenzo[de]isoquinoline-1,3-dione, often encountered in the field of organic chemistry, showcases a fascinating intersection of structural complexity and biological activity. This compound is part of a diverse category of isoquinoline derivatives, known for their role in various pharmacological applications.

Key Attributes:

  • Structural Diversity: The unique structure of 6-aminobenzo[de]isoquinoline-1,3-dione features a fused ring system that contributes to its stability and reactivity. This characteristic often leads to intriguing interaction profiles with biological molecules.
  • Pharmacological Potential: Compounds containing the isoquinoline framework are recognized for their diverse biological properties, including anticancer, antibacterial, and anti-inflammatory effects. Researchers are constantly exploring how structural modifications can enhance these properties.
  • Synthesis Pathways: The synthesis of 6-aminobenzo[de]isoquinoline-1,3-dione can employ various methods including cyclization reactions. Understanding the methodology opens avenues for creating derivatives with improved efficacy.

As noted by chemists, "The beauty of isoquinolines lies not only in their structure but also in their ability to interact with biological systems," emphasizing the potential applications in drug discovery. Further exploration of this compound can lead to innovative therapeutic agents.

Conclusion:

In summary, 6-aminobenzo[de]isoquinoline-1,3-dione is more than just a simple chemical entity; it is a testament to the intricate connections between chemistry and medicine. Its exploration could yield significant benefits in understanding complex biological processes and advancing therapeutic strategies.

Synonyms
4-Amino-1,8-naphthalimide
1742-95-6
4-Aminonaphthalimide
6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE
6-aminobenzo[de]isoquinoline-1,3-dione
6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
4-Aminonaphthalene-1,8-dicarboximide
1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino-
Naphthalimide, 4-amino-
4-amino1,8-naphthalimide
EINECS 217-110-1
MFCD00006921
6-Amino-1H-benz(de)isoquinoline-1,3(2H)-dione
BRN 0177185
S529AR2S8B
CHEBI:40071
1H-Benz(de)isoquinoline-1,3(2H)-dione, 6-amino-
CHEMBL338790
DTXSID6061941
4-22-00-06603 (Beilstein Handbook Reference)
6-AMINO-BENZO(DE)ISOQUINOLINE-1,3-DIONE
6-aminobenzo(de)isoquinoline-1,3-dione
DFP 1
6-amino-1H-benzo(de)isoquinoline-1,3(2H)-dione
2pax
Lopac-A-0966
4-ANI
UNII-S529AR2S8B
Lopac0_000063
SCHEMBL21124
BSPBio_001430
KBioGR_000150
KBioSS_000150
DTXCID3035559
BCBcMAP01_000231
BDBM27498
KBio2_000150
KBio2_002718
KBio2_005286
KBio3_000299
KBio3_000300
Bio1_000370
Bio1_000859
Bio1_001348
Bio2_000150
Bio2_000630
HMS1361H12
HMS1791H12
HMS1989H12
HMS3260M07
HMS3402H12
4-Amino-1,8-naphthalimide, 95%
4-Amino-1,8-naphthalimide, 96%
6-amino-1H-benz[de]isoquinoline-1
Tox21_500063
BBL027625
STK934866
AKOS005664748
CCG-204158
DB07096
FA67151
LP00063
SDCCGSBI-0050051.P002
IDI1_033900
NCGC00015035-01
NCGC00015035-02
NCGC00015035-03
NCGC00015035-04
NCGC00015035-05
NCGC00015035-06
NCGC00015035-07
NCGC00015035-08
NCGC00093577-01
NCGC00093577-02
NCGC00093577-03
NCGC00093577-04
NCGC00093577-05
NCGC00260748-01
4AN
AS-35824
HY-15276
PD002801
SY257978
DB-043973
CS-0003831
EU-0100063
NS00019549
A 0966
1H-Benzdeisoquinoline-1,3(2H)-dione, 6-amino-
6-amino-1H-benz[de]-isoquinoline-1,3(2H)-dione
SR-01000075200
SR-01000075200-1
6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione #
Amino-1,8-naphthalimide [4-Amino-1,8-naphthalimide]
BRD-K50214219-001-02-4
Q27096011
10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4-dione
217-110-1