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6-Aminonicotinamide

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Identification
Molecular formula
C6H7N3O
CAS number
329-89-5
IUPAC name
6-aminopyridine-3-carboxamide
State
State

At room temperature, 6-aminonicotinamide is in a solid state.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
381.00
Boiling point (Kelvin)
654.15
General information
Molecular weight
137.14g/mol
Molar mass
137.1410g/mol
Density
1.3860g/cm3
Appearence

6-Aminonicotinamide is a white to slightly beige crystalline solid. It is usually encountered as a powder and is stable under normal conditions.

Comment on solubility

Solubility of 6-aminopyridine-3-carboxamide

6-aminopyridine-3-carboxamide, a compound featuring a pyridine ring, exhibits interesting solubility properties that are worth exploring. The solubility of this compound can be influenced by various factors:

  • Polarity: Due to the presence of both amine and carboxamide functional groups, 6-aminopyridine-3-carboxamide is considered relatively polar, which enhances its solubility in polar solvents like water.
  • Hydrogen bonding: The ability of the carboxamide group to form hydrogen bonds contributes positively to its solubility in aqueous environments.
  • Solvent compatibility: This compound may also dissolve in various organic solvents, though its solubility might be lower compared to that in water.

In summary, it can be said that 6-aminopyridine-3-carboxamide has good solubility in polar solvents, especially water, facilitating its utility in various chemical applications. Understanding the solubility is crucial for its applications in pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about 6-Aminopyridine-3-carboxamide

6-Aminopyridine-3-carboxamide, often explored for its intriguing properties, is a versatile compound with substantial relevance in various fields of research and industry. Here are some noteworthy points about this compound:

  • Structure and Functionality: The structure of 6-aminopyridine-3-carboxamide consists of a pyridine ring substituted with an amino group and a carboxamide group, granting it unique chemical characteristics. This structure is key to its reactivity and interactions in biological systems.
  • Biological Significance: This compound plays a notable role as a precursor in the synthesis of pharmaceuticals. It has been studied for its potential application in treating neurological disorders due to its ability to enhance neurotransmitter release.
  • Research Applications: It's commonly used in chemical research and has applications in organic synthesis, contributing to the development of agrochemicals and drugs.
  • Potential Benefits: Studies indicate that 6-aminopyridine-3-carboxamide shows promise in improving neuronal function and may support recovery in nerve injuries. Such discoveries highlight its potential as a therapeutic agent.
  • Synthesis Pathways: The synthesis of this compound typically involves multi-step reactions, often utilizing readily available precursors which makes it accessible for laboratory research. This ease of synthesis encourages experimentation and innovation.

As a student or researcher in chemistry, understanding the properties and applications of 6-aminopyridine-3-carboxamide opens up exciting avenues for exploration. As we continue to unlock the mysteries of such compounds, their contributions to science and medicine become increasingly evident.

In the words of a prominent chemist, "The beauty of chemistry lies in its ability to transform the simplest of compounds into vital agents for change" – a perspective that rings true when considering compounds like 6-aminopyridine-3-carboxamide.

Synonyms
6-aminonicotinamide
329-89-5
6-Aminopyridine-3-carboxamide
2-Amino-5-carbamoylpyridine
3-PYRIDINECARBOXAMIDE, 6-AMINO-
6-Aminonikotinsaeureamid
6-amino-3-pyridinecarboxamide
6-Aminonicotinic acid amide
Nicotinamide, 6-amino-
Aminonicotinamide
FDA 0121
NSC 21206
6-Amino-nicotinsaeureamid
SR 4388
6-AN
CCRIS 7679
U-8774
6-Aminonikotinsaeureamid [German]
UNII-D6FNW67F2B
NSC21206
EINECS 206-349-7
6-ANA
D6FNW67F2B
BRN 0116042
DTXSID5051446
CHEBI:74514
AI3-50770
MFCD00006327
NSC-21206
DTXCID4030043
5-22-13-00618 (Beilstein Handbook Reference)
6 Aminonicotinamide
6-Aminonitoinamide
6-amino-nicotinamide
6-Amino nicotinamide
Spectrum2_001709
Spectrum3_001976
NCIMech_000769
WLN: T6NJ BZ EVZ
6-Aminonicotinamide, 99%
BSPBio_003576
MLS002207034
2-Aminopyridine-5-carboxamide
SCHEMBL105510
SPECTRUM1505315
SPBio_001698
6-azanylpyridine-3-carboxamide
Nicotinamide, 6-amino-(8CI)
CHEMBL1324108
KBio3_002955
BDBM225673
GTC000445A
HMS3865N03
ALBB-025399
Tox21_303956
BBL104231
CCG-35857
s9783
STL558250
AKOS003406190
CS-W011058
FA06269
HY-W010342
NCGC00095299-01
NCGC00095299-02
NCGC00095299-03
NCGC00357190-01
AC-31893
BP-13037
CAS-329-89-5
NCI60_001784
PD000946
SMR001306701
SY038238
TS-00033
DB-048308
A0986
NS00029399
6-AMINO-3-PYRIDINECARBOXYLIC ACID AMIDE
EN300-1257643
A821549
Q26841298
Z959893184
206-349-7
4FG