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6-Azaspiro[3.4]octane-5,7-dione

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Identification
Molecular formula
C7H9NO2
CAS number
19840-53-2
IUPAC name
6-azaspiro[3.4]octane-5,7-dione
State
State

At room temperature, 6-Azaspiro[3.4]octane-5,7-dione exists as a solid. It is stable under normal conditions and not much prone to moisture uptake.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
139.15g/mol
Molar mass
139.1540g/mol
Density
1.2650g/cm3
Appearence

The compound appears as a white crystalline solid. The crystalline structure is characterized by the spiro linkage which forms a distinctive three-dimensional framework.

Comment on solubility

Solubility of 6-azaspiro[3.4]octane-5,7-dione

6-azaspiro[3.4]octane-5,7-dione, a bicyclic compound, exhibits interesting solubility characteristics that can be influenced by several factors. Understanding its solubility is crucial for applications in medicinal chemistry and material sciences. Here are some important points regarding its solubility:

  • Solvent Interaction: The solubility of this compound can vary significantly depending on the solvent in which it is dissolved. Common solvents include water, ethanol, and dimethyl sulfoxide (DMSO).
  • Polarity: Being a nitrogen-containing heterocycle, 6-azaspiro[3.4]octane-5,7-dione may show increased solubility in polar solvents due to its potential for hydrogen bonding.
  • Temperature Effects: The solubility will also likely increase with temperature, as many organic compounds tend to dissolve better at elevated temperatures due to increased molecular movement.
  • pH Influence: The solubility can be affected by the pH of the solution, as certain functional groups may become protonated or deprotonated, altering their solubility behavior.

In summary, the solubility of 6-azaspiro[3.4]octane-5,7-dione is not strictly defined and exhibits dependency on solvent type, temperature, and pH. For optimal use in applications, it is essential to conduct solubility tests in specific conditions to assess its behavior thoroughly.

Interesting facts

Interesting Facts about 6-azaspiro[3.4]octane-5,7-dione

6-azaspiro[3.4]octane-5,7-dione is a fascinating compound with unique structural characteristics and potential applications. Here are some intriguing facts:

  • Structural Uniqueness: The compound features a spiro bicyclic structure, which is a rare occurrence in organic chemistry. This unique configuration contributes to its interesting chemical properties.
  • Versatility: 6-azaspiro[3.4]octane-5,7-dione serves as a versatile building block in synthetic organic chemistry. It can be used to create various derivatives, which may possess different biological activities.
  • Potential Biological Activity: Some derivatives of spiro compounds have demonstrated promising pharmacological activities, including anti-inflammatory and antimicrobial properties. Researchers are investigating whether 6-azaspiro[3.4]octane-5,7-dione might open new avenues in drug discovery.
  • Research Interest: Due to its unique structure, there's ongoing research focused on the synthesis and application of this compound in medicinal chemistry. Scientists are eager to explore the interactions and efficacy of such spiro compounds in biological systems.
  • Chemical Reactions: The presence of carbonyl groups in its structure indicates potential reactivity with nucleophiles, making it an interesting target for further chemical modifications.

As we continue to advance in synthetic methods and broaden our understanding of spiro compounds, 6-azaspiro[3.4]octane-5,7-dione stands out as a compound to watch in future research, with the possibility of uncovering new materials and therapeutics.

Synonyms
6-Azaspiro[3.4]octane-5,7-dione
1497-16-1
LD 4070
6-Azaspiro(3.4)octane-5,7-dione
EINECS 216-090-1
BRN 1525974
Aza-6-spiro(3,4)octane-dione-5,7 [French]
Aza-6-spiro(3,4)octane-dione-5,7
DTXSID70164365
5-21-10-00068 (Beilstein Handbook Reference)
DTXCID4086856
216-090-1
JIGMIHMXIINUHH-UHFFFAOYSA-N
BAA49716
AKOS006277626
NS00044989
EN300-222726
Z1198157427