6-Benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole

Identification

Molecular formula

C₂₁H₂₂N₂

IUPAC name

6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole

State

This compound is solid at room temperature, usually forming crystalline structures that can vary in size.

Melting point (Celsius)

110.00

Melting point (Kelvin)

383.15

Boiling point (Celsius)

375.00

Boiling point (Kelvin)

648.15

General information

Molecular weight

286.42g/mol

Molar mass

286.3820g/mol

Density

1.2300g/cm³

Appearence

6-Benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole typically appears as a solid crystalline substance. The appearance can vary from colorless to pale yellow, depending on the specific purity and handling conditions of the compound.

Comment on solubility

Solubility of 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole

The solubility of 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole can be characterized by several factors. Although detailed experimental solubility data may vary, some general observations can be made:

Polarity: This compound exhibits a non-polar nature due to the presence of aromatic and aliphatic components, which may limit its solubility in polar solvents like water.
Solvent Interactions: It tends to dissolve better in organic solvents such as chloroform, methanol, and dimethyl sulfoxide (DMSO).
Temperature Effect: Increasing temperature can enhance solubility in many organic solvents, promoting greater interaction between solutes and solvents.
Potential Applications: Understanding its solubility is crucial for its application in fields like pharmaceuticals, where bioavailability and formulation efficiency depend heavily on solubility characteristics.

In summary, although specific quantitative solubility data might not be readily available, the general trends suggest that 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole is more soluble in organic solvents rather than in water. This characteristic makes it essential for various applications, especially where organic solutions are preferred.

Interesting facts

Interesting Facts about 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole

6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole is a fascinating compound that stands at the intersection of synthetic organic chemistry and pharmacology. Here are some interesting facts about this intriguing molecule:

Complex Structure: The name of this compound reflects its intricate structure, featuring a fused ring system that incorporates both an indole moiety and an azepine component. Such a combination can often result in unique biological properties.
Potential Pharmacological Applications: Compounds similar to 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole have been investigated for their potential roles as:
- Antidepressants
- Antipsychotics
- Ligands for neuroreceptors
Research and Development: This compound serves as a valuable scaffold in drug discovery. Researchers often modify the benzyl group to explore variations in activity and selectivity against specific biological targets.
Interdisciplinary Connections: The synthesis and study of this compound often require an understanding of:
- Organic synthesis techniques
- Medicinal chemistry
- Pharmacodynamics and pharmacokinetics
Chirality and Isomerism: The tetrahydro part of this compound introduces chirality, which is crucial in many biological interactions. Investigating the different stereoisomers can reveal how small changes can have significant effects on activity.

In conclusion, 6-benzyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole exemplifies the complexities of chemical research where structure directly influences function. As scientists and students explore its properties, we continue to deepen our understanding of how these intricate connections can lead to novel therapeutic agents.

Synonyms

SCHEMBL6038295