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6-Benzyloxy-5-methoxyindole

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Identification
Molecular formula
C16H15NO2
CAS number
NA
IUPAC name
6-benzyloxy-5-methoxy-1H-indole
State
State

At room temperature, 6-Benzyloxy-5-methoxyindole exists as a solid. It is generally stable under standard conditions of temperature and pressure.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.00
General information
Molecular weight
281.33g/mol
Molar mass
281.3290g/mol
Density
1.2200g/cm3
Appearence

6-Benzyloxy-5-methoxyindole typically appears as an off-white to pale yellow solid. The compound may form crystalline structures depending on its purity and specific conditions of handling.

Comment on solubility

Solubility of 6-benzyloxy-5-methoxy-1H-indole

6-benzyloxy-5-methoxy-1H-indole, a compound featuring both aromatic and methoxy groups, exhibits interesting solubility characteristics that are important for various applications. Understanding its solubility can provide insights into its behavior in different environments:

  • Solvent Compatibility: The compound is likely to be soluble in organic solvents due to its nonpolar aromatic structure. Common solvents that may dissolve this compound include:
    • Dichloromethane
    • Ethyl acetate
    • Chloroform
  • Water Solubility: Due to the methoxy groups present, the compound may have limited solubility in water. The hydrophobic character of the benzyl and indole portions can further decrease its affinity for polar solvents like water.
  • Influencing Factors: Factors that can affect solubility include:
    • Temperature: Increased temperature typically enhances solubility for many organic compounds.
    • pH: The ionization state of the compound can influence its solubility in various solvents.
    • Presence of other solutes: The solubility can be affected by the presence of salts or other solubilizing agents.

In conclusion, while 6-benzyloxy-5-methoxy-1H-indole demonstrates a tendency to dissolve in organic solvents, its solubility in water is expected to be quite limited. This behavior is crucial for its applications in synthesis and pharmacological contexts, where solubility can dictate bioavailability and interaction with biological systems.

Interesting facts

Interesting Facts About 6-Benzyloxy-5-Methoxy-1H-Indole

6-Benzyloxy-5-methoxy-1H-indole is a fascinating compound that belongs to the indole family, which is known for its wide array of biological activities and applications. Here are some captivating insights about this particular compound:

  • Structure and Function: The indole structure is characterized by a fused benzene and pyrrole ring, which plays a crucial role in the compound's reactivity and biological interactions.
  • Biological Significance: Indole derivatives, including this compound, are often studied for their pharmacological properties. They show potential as anti-cancer agents, anti-inflammatory agents, and even in treating neurological disorders.
  • Natural Occurrences: Many indole compounds are naturally occurring and can be found in a variety of plants and fungi. This suggests potential avenues for exploring natural products as sources for medicinal compounds.
  • Research Applications: Scientists are increasingly interested in indole derivatives for their role in drug design and development due to their ability to mimic the structure of neurotransmitters.
  • Synthetic Versatility: The synthesis of 6-benzyloxy-5-methoxy-1H-indole can involve multiple synthetic pathways, showcasing the versatility in organic synthesis techniques.

In conclusion, 6-benzyloxy-5-methoxy-1H-indole represents a compelling area of study within the realm of organic chemistry and pharmacology. As research progresses, the unique properties and potential applications of this compound may lead to breakthroughs in therapeutic strategies and drug development.

Synonyms
6-Benzyloxy-5-methoxyindole
2426-59-7
1H-Indole, 5-methoxy-6-(phenylmethoxy)-
INDOLE, 6-(BENZYLOXY)-5-METHOXY-
NSC 92528
M053B32CSE
5-Methoxy-6-(phenylmethoxy)-1H-indole
NSC-92528
UNII-M053B32CSE
6-benzyloxy-5-methoxy-1h-indole
DTXSID20178957
DTXCID80101448
1H-Indole, 5-methoxy-6-(phenylmethoxy)-(9CI)
ypramyrrnnygse-uhfffaoysa-n
6-(Benzyloxy)-5-methoxy-1H-indole
5-methoxy-6-phenylmethoxy-1H-indole
NSC92528
NCIOpen2_005973
SCHEMBL187757
AKOS027447631
6-(Benzyloxy)-5-methoxy-1H-indole #
DS-19077
DB-091016
CS-0061920
F52633