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Thioflavin T

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Identification
Molecular formula
C17H19Br2IN2S2
CAS number
2390-54-7
IUPAC name
6-bromo-2-[5-(6-bromo-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole;iodide
State
State

At room temperature, Thioflavin T is a solid.

Melting point (Celsius)
318.00
Melting point (Kelvin)
591.00
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.00
General information
Molecular weight
670.56g/mol
Molar mass
670.5560g/mol
Density
0.7100g/cm3
Appearence

Thioflavin T appears as a pale yellow to yellow-green crystalline powder. It is known for its fluorescent properties, especially upon binding to amyloid structures, where it exhibits a strong enhancement in fluorescence.

Comment on solubility

Solubility of 6-bromo-2-[5-(6-bromo-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; iodide

The solubility of the compound 6-bromo-2-[5-(6-bromo-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; iodide is influenced by several factors that are common in complex organic compounds. Here are some significant points to consider:

  • Polarity: The presence of charged groups, such as the iodide ion, suggests that the compound may exhibit some degree of solubility in polar solvents like water, although its overall structure is predominantly organic.
  • Solvent Interaction: Typically, compounds with significant aromatic rings, such as benzothiazoles, can show variable solubility in non-polar solvents due to their hydrophobic characteristics.
  • Temperature Dependency: Solubility can increase with temperature, and thus, testing in varying thermal conditions may reveal different solubility profiles.
  • Experimental Data: Always refer to empirical data for precise details on solubility as theoretical predictions may not fully account for all intermolecular interactions.

As a takeaway, understanding the solubility of this compound necessitates a comprehensive examination of both its structural features and the solvents used. Each factor can significantly impact its behavior in various environments, making solubility a dynamic characteristic worthy of exploration!

Interesting facts

Interesting Facts About 6-Bromo-2-[5-(6-bromo-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; Iodide

This compound, known for its complex structure, is an intriguing member of the benzothiazole family, often studied for its unique chemical properties and potential applications. Here are some notable facts:

  • Pharmaceutical Potential: Compounds containing the benzothiazole moiety are often explored for their pharmaceutical applications. They exhibit various biological activities, including antimicrobial, anticancer, and anti-inflammatory properties.
  • Structural Complexity: The presence of multiple bromine substitutions enhances the electronic properties of this compound, which can affect its reactivity and stability. This functionalization often leads to enhanced interactions with biological targets.
  • Research Interest: Due to its unique structure, researchers are keen on synthesizing derivatives of this compound. Such studies can lead to the discovery of new materials with specific electrical, optical, or catalytic properties.
  • Method of Synthesis: The synthetic pathways leading to this compound often involve multistep reactions, showcasing the ingenuity of modern organic chemistry. Techniques like halogenation, coupling reactions, and condensation can play crucial roles.
  • Environmental Impact: Understanding the stability and degradation of such compounds in environmental conditions is essential. Studies could shed light on their behavior in biological systems and ecosystems.

As synthesized compounds continue to hold promise in various fields, exploration of this particular benzothiazole derivative highlights the exquisite relationship between structure and function in chemistry.

Synonyms
6-Bromo-2-[5-(6-bromo-3-methyl-1,3-benzothiazol-2(3H)-ylidene)penta-1,3-dien-1-yl]-3-methyl-1,3-benzothiazol-3-ium iodide
DTXSID50932786