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6-Bromo-3-(2-pyridyl)coumarin

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Identification
Molecular formula
C14H8BrNO2
CAS number
4290-31-5
IUPAC name
6-bromo-3-(2-pyridyl)chromen-2-one
State
State

At room temperature, 6-Bromo-3-(2-pyridyl)coumarin is typically found in a solid state as it is a crystalline powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
379.00
Boiling point (Kelvin)
652.00
General information
Molecular weight
286.13g/mol
Molar mass
286.0890g/mol
Density
1.5800g/cm3
Appearence

6-Bromo-3-(2-pyridyl)coumarin appears as a yellow crystalline powder. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone.

Comment on solubility

Solubility of 6-bromo-3-(2-pyridyl)chromen-2-one

The solubility of 6-bromo-3-(2-pyridyl)chromen-2-one can be an intriguing topic of study due to its unique structure and potential applications in various fields. Here are a few key points regarding its solubility:

  • Solvent Dependency: The solubility of this compound can vary significantly depending on the solvent used. Generally, it is expected to be soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, while it may have limited solubility in water.
  • Polarity Considerations: The presence of the pyridine ring contributes to the overall polarity of the molecule, which can influence its solubility in polar versus non-polar solvents.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature, making the compound potentially more soluble at elevated temperatures.
  • pH Influence: The solubility may also be affected by pH adjustments, especially if the compound possesses any functional groups that can ionize.

In summary, the solubility of 6-bromo-3-(2-pyridyl)chromen-2-one is multifaceted and influenced by various factors including the choice of solvent, temperature, and pH conditions. Understanding these nuances allows for better handling and application of this compound in chemical research and industry.

Interesting facts

Interesting Facts about 6-bromo-3-(2-pyridyl)chromen-2-one

6-bromo-3-(2-pyridyl)chromen-2-one is a fascinating compound belonging to the class of chromones, which are known for their diverse biological activities and intriguing chemical characteristics. Here are some interesting insights into this compound:

  • Structural Uniqueness: The presence of a bromine atom at the 6-position and a 2-pyridyl group at the 3-position enhances the structural complexity of this compound, potentially affecting its reactivity and interactions.
  • Biological Significance: Compounds related to chromones have been studied extensively for their pharmacological properties, including anti-inflammatory, antioxidant, and antimicrobial effects. Some studies suggest that such derivatives may even exhibit promising anticancer properties.
  • Synthetic Relevance: The synthesis of 6-bromo-3-(2-pyridyl)chromen-2-one often involves intricate reactions, allowing chemists to explore various synthetic pathways and improve upon established methodologies.
  • Applications: Beyond medicinal chemistry, this compound can serve as a vital building block for creating libraries of compounds for drug discovery and development. Its functional groups lend themselves well to further modifications.
  • In Research: As a subject of ongoing research, 6-bromo-3-(2-pyridyl)chromen-2-one's interactions with specific biological targets continue to be explored, highlighting the compound's potential in therapeutic interventions.

In conclusion, 6-bromo-3-(2-pyridyl)chromen-2-one represents a small yet significant piece of the larger puzzle in organic and medicinal chemistry, demonstrating the endless possibilities contained within the realm of chemical compounds.

Synonyms
958-58-7
6-Bromo-3-(2-pyridyl)coumarin
BRN 0884139
COUMARIN, 6-BROMO-3-(2-PYRIDYL)-
DTXSID30241964
DTXCID60164455
6-bromo-3-(pyridin-2-yl)-2H-chromen-2-one
6-BROMO-3-(PYRIDIN-2-YL)-CHROMEN-2-ONE
Oprea1_202697