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6-Chlorobenzothiazol-2-amine

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Identification
Molecular formula
C7H5ClN2S
CAS number
1563-60-0
IUPAC name
6-chloro-1,3-benzothiazol-2-amine
State
State

At room temperature, 6-Chlorobenzothiazol-2-amine is in a solid state. It is often handled in powder form for experimental and industrial applications.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.20
Boiling point (Celsius)
327.80
Boiling point (Kelvin)
600.80
General information
Molecular weight
184.64g/mol
Molar mass
184.6400g/mol
Density
1.4640g/cm3
Appearence

6-Chlorobenzothiazol-2-amine is typically a crystalline solid which may appear as a powder. The color can vary from pale yellow to light brown depending on purity and specific handling conditions.

Comment on solubility

Solubility of 6-chloro-1,3-benzothiazol-2-amine

The solubility of 6-chloro-1,3-benzothiazol-2-amine can be quite interesting and is influenced by several factors such as temperature, solvent choice, and chemical structure. This compound is classified as a heterocyclic aromatic amine, primarily containing both nitrogen and sulfur, which can affect its interactions with solvents.

Solubility Characteristics:

  • Solvent Dependence: The solubility generally varies dramatically between polar and non-polar solvents.
  • Polar Solvents: It tends to exhibit higher solubility in polar solvents like water or alcohols due to the ability to engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, solubility might decrease in non-polar solvents where the interaction is limited.

Moreover, it is important to note that temperature plays a significant role. As the temperature increases, the kinetic energy of the molecules increases, often leading to enhanced solubility. Therefore, under elevated temperatures, you might observe a better dissolution of 6-chloro-1,3-benzothiazol-2-amine.

In the context of chemical applications, understanding the solubility profile of this compound is crucial, as it impacts reactivity and potential uses in various formulations.

Interesting facts

Interesting Facts about 6-Chloro-1,3-benzothiazol-2-amine

6-Chloro-1,3-benzothiazol-2-amine is a fascinating compound with several intriguing attributes that highlight its significance in chemical research. This compound belongs to the class of benzothiazoles, which are known for their diverse biological activities and applications in various fields.

Key Features

  • Biological Importance: Benzothiazole derivatives have been extensively studied for their pharmacological properties, including antibacterial, antifungal, and anticancer activities.
  • Role in Drug Development: The presence of the chloro substituent enhances the compound's potency, making it a target for synthesis in medicinal chemistry.
  • Versatile Synthetic Pathways: There are multiple methods for synthesizing 6-chloro-1,3-benzothiazol-2-amine, allowing for flexibility in its production.

Applications

This compound is particularly notable for its use in several areas:

  • Agriculture: Compounds like 6-chloro-1,3-benzothiazol-2-amine are explored for use in developing agrochemicals.
  • Material Science: Researchers investigate its potential in creating advanced materials due to its structural properties.
  • Environmental Chemistry: The compound’s derivatives are studied in the context of environmental pollutants and their degradation.

Fun Fact

It's interesting to note that compounds like 6-chloro-1,3-benzothiazol-2-amine often serve as lead compounds in drug design. This means they can inspire further research for new therapeutic agents, influencing the creation of more effective treatments.

Overall, 6-chloro-1,3-benzothiazol-2-amine exemplifies the crucial role that organic compounds play in advancing science, particularly in the realms of medicine and technology. As research continues, the potential applications of this compound may uncover even more fascinating discoveries in the future.

Synonyms
2-Amino-6-chlorobenzothiazole
95-24-9
6-Chlorobenzothiazol-2-ylamine
6-Chloro-1,3-benzothiazol-2-amine
2-Benzothiazolamine, 6-chloro-
6-chlorobenzo[d]thiazol-2-amine
6-Chloro-2-benzothiazolamine
2-Amino-6-chloro-1,3-benzothiazole
BENZOTHIAZOLE, 2-AMINO-6-CHLORO-
EINECS 202-402-3
6-chloro-2-aminobenzothiazole
BRN 0127752
2U337T5UFG
6-Chloro-benzothiazol-2-ylamine
MFCD00053557
6-chloro-1,3-benzothiazol-2-ylamine
2-AMINO-6-CHLOROBENZO[D]THIAZOLE
DTXSID4059120
4-27-00-04862 (Beilstein Handbook Reference)
6-CHLORO-2-BENZOTHIAZOLYLAMINE
6-CHLOROBENZO(D)THIAZOL-2-AMINE
54T
Maybridge1_001187
UNII-2U337T5UFG
SCHEMBL77839
MLS001005225
BIDD:GT0846
CHEMBL97643
2-amino-6-chloro-benzothiazole
6-chloro-2-amino benzothiazole
6-chloro-2-benzothiazole-amine
DTXCID7048950
HMS544N21
HMS2666D12
ALBB-000206
BCP27085
STR07530
AC-037
CCG-51735
GEO-02880
STK071371
2-Amino-6-chlorobenzothiazole, 99%
AKOS000104169
PS-8511
6-Chloro-1,3-benzothiazol-2-amine #
NCGC00246061-01
SMR000348635
SY014143
6-chloro-1,3-benzothiazol-2-amine (BT1)
DB-027790
A1216
CS-0040190
NS00022903
EN300-17160
D70122
AE-641/00127046
SR-01000641019-1
Q27455470
Z56896352
F1911-0017
InChI=1/C7H5ClN2S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10