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6-Chloropurine

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Identification
Molecular formula
C5H4ClN5
CAS number
87-42-3
IUPAC name
6-chloro-1H-purin-2-amine
State
State

At room temperature, 6-Chloropurine is a solid.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
169.57g/mol
Molar mass
169.5590g/mol
Density
1.4730g/cm3
Appearence

6-Chloropurine appears as a white to off-white crystalline powder. It is largely recognized for its use in biochemistry and organic chemistry research, where it serves as a building block in the synthesis of more complex chemicals.

Comment on solubility

Solubility of 6-chloro-1H-purin-2-amine

6-chloro-1H-purin-2-amine, with the chemical formula C5H4ClN5, exhibits distinct solubility characteristics that are crucial for its application in various chemical and biological contexts.

Key Points about Solubility:

  • Solvent Affinity: This compound is expected to be soluble in polar solvents such as water due to the presence of amino and chlorine groups, which can engage in hydrogen bonding.
  • Insolubility in Non-polar Solvents: Conversely, 6-chloro-1H-purin-2-amine is likely to have very low solubility in non-polar solvents, such as hexane or benzene, due to its polar functional groups.
  • pH Dependency: The solubility may vary with changes in pH, as transformations in its protonation state could influence its interaction with solvents.
  • Temperature Effects: Increased temperature may enhance its solubility slightly, which is a common behavior among many crystalline compounds.

In conclusion, the solubility profile of 6-chloro-1H-purin-2-amine is shaped by its molecular structure and functional groups, making it crucial to consider these factors when utilizing the compound in research and industrial applications.

Interesting facts

Interesting Facts about 6-Chloro-1H-purin-2-amine

6-Chloro-1H-purin-2-amine, often referred to as a derivative of purine, holds a unique position in the study of nucleic acids and related biochemistry. Here are some fascinating insights about this compound:

  • Structure and Significance: As a chlorinated purine derivative, 6-chloro-1H-purin-2-amine plays a crucial role in the synthesis of various nucleosides and nucleotides, essential components in the field of genetics.
  • Biological Impact: Compounds like this one are significant in pharmacology, particularly in developing antiviral and anticancer agents. Understanding their mechanisms can contribute to novel therapeutic approaches.
  • Research Utility: This compound can be utilized in research settings to study the interactions of purines with DNA and RNA, potentially leading to advancements in genetic engineering and molecular biology.
  • Synthesis: The synthesis of 6-chloro-1H-purin-2-amine often involves intricate organic reactions, showcasing the beauty and complexity of organic chemistry.

In the words of a prominent chemist:

“Understanding the derivatives of purines opens doors to unraveling the mysteries of life at a molecular level.”

Overall, 6-chloro-1H-purin-2-amine exemplifies the connection between chemical structure and biological function, making it an intriguing compound for further exploration in various scientific fields.