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6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole

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Identification
Molecular formula
C10H4ClF7N2
CAS number
153463-89-9
IUPAC name
6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole
State
State

At room temperature, this compound is typically found in a solid state. It may exist in powder or crystalline form, depending on the method of preparation or formulation.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.00
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.00
General information
Molecular weight
308.59g/mol
Molar mass
308.6000g/mol
Density
1.5300g/cm3
Appearence

This compound appears as a white to off-white solid or powder. Its exact appearance can vary depending on its specific formulation or hydration state, but it generally retains a consistent solid-state under standard conditions.

Comment on solubility

Solubility of 6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole

The solubility of 6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole can be influenced by a variety of factors due to its unique molecular structure. Here are some key considerations:

  • Polar vs. Nonpolar: This compound contains both polar and nonpolar characteristics, which can affect its interaction with solvents. The presence of the chlorinated and fluorinated groups contributes to its hydrophobic nature.
  • Temperature Dependency: Like many organic compounds, its solubility can increase with temperature. Higher temperatures may disrupt intermolecular interactions and allow for greater dissolution.
  • Solvent Selection: Compatibility with solvents varies significantly. Typically, it exhibits better solubility in nonpolar solvents such as:
    • Hexane
    • Chloroform
    • Ethyl acetate
  • Environmental Impact: The presence of fluorine atoms can lead to concerns regarding solubility in environmental contexts, as these molecules can be persistent in nature.

In summary, understanding the solubility profile of 6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole requires a thoughtful approach to solvent choice, temperature considerations, and an awareness of its unique chemical properties.

Interesting facts

Interesting Facts about 6-Chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole

6-Chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole is a fascinating compound that combines the structural properties of benzimidazole with the unique characteristics imparted by fluorinated groups. Here are some intriguing aspects of this compound:

Unique Structural Features

  • Fluorination: The presence of multiple fluorine atoms significantly alters the chemical reactivity and physical properties of the compound, leading to enhanced stability and distinct polar characteristics.
  • Benzimidazole Core: This core structure is known for its diverse biological activities, with many benzimidazole derivatives exhibiting pharmaceutical relevance, particularly as anti-parasitic agents.

Applications and Uses

  • Pharmaceutical Research: Due to its unique structural features, this compound may serve as a lead compound in drug development, particularly for targeting specific biological pathways.
  • Material Science: The fluorinated groups could provide enhanced properties for use in high-performance materials or coatings due to their chemical resistance.

Environmental Impact

The use of fluorinated compounds has raised attention due to their environmental persistence. As a work in progress, exploring greener alternatives to such compounds is crucial for sustainable practices in chemical synthesis.

Chemical Properties

In terms of chemical properties, benzimidazole compounds, including this one, often exhibit:

  • Acidic behavior due to the nitrogen atoms in the imidazole ring.
  • Activity against various biological targets, making them valuable in medicinal chemistry.

In conclusion, 6-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole represents a vibrant intersection of chemistry and biology, with its unique structure offering vast potential in both research and application. The continual investigation into such compounds contributes significantly to advancements in multiple scientific fields.

Synonyms
BENZIMIDAZOLE, 5(or 6)-CHLORO-2-(HEPTAFLUOROPROPYL)-
6866-58-6
BRN 0561403
5(or 6)-Chloro-2-(heptafluoropropyl)benzimidazole
DTXSID80218808
5-Chloro-2-(heptafluoropropyl)benzimidazole
NS00111558
5-chloro-2-(1,1,2,2,3,3,3-heptafluoropropyl)-1H-benzimidazole