Skip to main content

Thioflavin T

ADVERTISEMENT
Identification
Molecular formula
C17H19ClN2SCI
CAS number
2390-54-7
IUPAC name
6-chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole;iodide
State
State

At room temperature, Thioflavin T is a solid substance.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.20
Boiling point (Celsius)
275.90
Boiling point (Kelvin)
549.10
General information
Molecular weight
480.96g/mol
Molar mass
480.9600g/mol
Density
1.7708g/cm3
Appearence

Thioflavin T is typically a yellow crystalline substance. It may appear as a powder that is sensitive to light. When dissolved in solution, it exhibits fluorescence properties, making it useful in various biochemical assays.

Comment on solubility

Solubility of 6-chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; iodide

The solubility of a compound can significantly affect its usage and behavior in various applications. For the compound 6-chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; iodide, several factors influence its solubility:

  • Polarity: The presence of iodide suggests increased ionic character, which can enhance solubility in polar solvents such as water.
  • Functional Groups: The benzothiazole structure may contribute to solubility in nonpolar or mildly polar organic solvents, due to its aromatic rings.
  • Temperature Dependency: The solubility often increases with temperature, which may be essential to consider during dissolution.
  • Solvent Matching: Choosing the right solvent is crucial; polar solvents will likely increase solubility, while nonpolar solvents may reduce it.

In summary, while this compound may exhibit varying solubility depending on the solvent and temperature conditions, its ionic substitution with iodide suggests a tendency for better solubility in polar environments. Careful experimentation is necessary to determine its exact solubility profile.

Interesting facts

Interesting Facts about 6-Chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; Iodide

This compound is a fascinating member of the benzothiazole family, which is known for its extensive applications in various fields, particularly in medicinal chemistry and materials science.

1. Unique Structural Elements

The structural features of this compound include:

  • Chlorine Substituents: The presence of multiple chlorine atoms contributes to the compound's reactivity and potential biological activity.
  • Benzothiazole Framework: This framework provides a robust backbone that is essential in the development of various pharmacologically active compounds.
  • Complex Side Chains: The long penta-2,4-dienylidene side chain significantly affects the stability and electronic properties of the compound.

2. Role in Drug Development

Compounds with the benzothiazole structure have been extensively studied for their:

  • Antimicrobial Properties: Many derivatives have shown effectiveness against a range of pathogenic organisms.
  • Anticancer Activity: Some studies suggest that similar compounds can inhibit the growth of cancer cells.
  • Potential as Diagnostic Agents: Researchers are exploring its use in imaging and diagnostic applications.

3. Importance in Organic Synthesis

The synthesis of this compound utilizes robust methods of organic chemistry, including:

  • Multi-Step Synthesis: The creation of complex molecules often involves several synthetic steps, showcasing the intricacy of chemistry.
  • Catalysis: This compound's synthesis might incorporate catalysts to enhance reaction efficiency.

4. Future Prospects

As a scientist or chemistry student, exploring the potential of this compound opens avenues for:

  • Drug Modification: Tailoring the compound can yield new therapeutic agents.
  • Material Science: Investigating its use in photonic materials or sensors.

In summary, the intricate structure and potential applications of 6-chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole; iodide illustrate why compounds like these are a central focus in contemporary research. With continued study, this compound might provide solutions to critical health and technological challenges.

Synonyms
14795-77-8
6,6'-Dichloro-3,3'-dimethylthiadicarbocyanine iodide
6,6'-Dichloro-3,3'-dimethylpentamethinethiacyanine iodide
Benzothiazolium, 6-chloro-2-(5-(6-chloro-3-methyl-2-benzothiazolinylidene)-1,3-pentadienyl)-3-methyl-, iodide
6-Chloro-2-[5-(6-chloro-3-methyl-1,3-benzothiazol-2(3H)-ylidene)penta-1,3-dien-1-yl]-3-methyl-1,3-benzothiazol-3-ium iodide
DTXSID20933260