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6-Chloro-2-methoxyacridin-9-amine

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Identification
Molecular formula
C14H11ClN2O
CAS number
78472-63-6
IUPAC name
6-chloro-2-methoxy-acridin-9-amine
State
State

At room temperature, 6-Chloro-2-methoxyacridin-9-amine is a solid. The compound is stable under normal conditions, but precaution should be taken to avoid moisture and light exposure as it can degrade the quality of the compound.

Melting point (Celsius)
227.00
Melting point (Kelvin)
500.15
Boiling point (Celsius)
462.00
Boiling point (Kelvin)
735.15
General information
Molecular weight
274.70g/mol
Molar mass
274.7190g/mol
Density
1.3600g/cm3
Appearence

6-Chloro-2-methoxyacridin-9-amine typically appears as a yellow to orange solid. Its crystal structure can be observed under a microscope, revealing intricate lattice arrangements typical for acridine derivatives.

Comment on solubility

Solubility of 6-chloro-2-methoxy-acridin-9-amine

The solubility of 6-chloro-2-methoxy-acridin-9-amine can be influenced by several factors, including temperature, pH, and the presence of other solvents. While specific solubility data for this compound is not extensively documented, we can discuss some general principles relevant to its class of compounds.

  • Polar vs. Nonpolar Solvents: This compound has both polar (due to the methoxy group) and nonpolar (due to the acridine core) characteristics. As such, it may exhibit better solubility in polar organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Temperature: Generally, solubility increases with temperature, which is an important consideration for dissolution processes. Higher temperatures can help overcome the energy barrier for solvation.
  • pH Sensitivity: The solubility may be affected by the pH of the solution, especially if the compound can exist in ionized forms under certain conditions.

In summary, while direct solubility values may be limited, it can be hypothesized that 6-chloro-2-methoxy-acridin-9-amine is likely to be soluble in polar organic solvents. Understanding its behavior in various environments can help in predicting its solubility characteristics effectively.

Interesting facts

Interesting Facts about 6-Chloro-2-methoxy-acridin-9-amine

6-Chloro-2-methoxy-acridin-9-amine is a compound that has gained attention in both academic and industrial research due to its unique properties and potential applications. Here are some fascinating insights into this intriguing compound:

  • Structural Diversity: This compound belongs to the acridine family, which is known for its diverse structural properties. Acridines are heterocyclic compounds that possess a tricyclic structure, making them versatile in various chemical reactions.
  • Biological Activity: Compounds in the acridine class are often investigated for their biological activities. Research suggests that 6-chloro-2-methoxy-acridin-9-amine shows potential as an antimicrobial and antitumor agent, indicating its usefulness in pharmaceutical applications.
  • Fluorescent Properties: Like many acridine derivatives, this compound is likely to exhibit fluorescence. This characteristic makes it valuable in biological imaging and fluorescent labeling, enabling scientists to visualize cellular processes in real-time.
  • Synthetic Pathways: Synthesis of this compound can involve multiple steps, including chlorination and methoxylation reactions. Understanding these pathways is crucial for chemists looking to optimize yields and create derivatives with enhanced properties.
  • Potential in Education: For students of chemistry, 6-chloro-2-methoxy-acridin-9-amine serves as an excellent example of how subtle changes in chemical structure can lead to significant differences in activity and application.
  • Environmental Considerations: As with many synthetic compounds, researchers are increasingly focused on examining the environmental impact of acridine derivatives, ensuring that minor modifications do not lead to significant ecological harm.

Overall, 6-chloro-2-methoxy-acridin-9-amine is more than just a chemical compound; it is a gateway to exploring complex interactions within biological systems and the rich realm of synthetic organic chemistry.

Synonyms
9-Amino-6-chloro-2-methoxyacridine
6-Chloro-2-methoxy-9-acridinamine
NSC 15300
G 185
9-Acridinamine, 6-chloro-2-methoxy-
ACRIDINE, 9-AMINO-3-CHLORO-7-METHOXY-
Acridine, 9-amino-6-chloro-2-methoxy-
2-methoxy-6-chloro-9-aminoacridine
9-amino-2-methoxy-6-chloroacridine
9-amino-3-chloro-7-methoxyacridine
BRN 0226315
DTXSID90188987
5-Amino-2-chloro-7-methoxyacridine (European)
DTXCID50111478
9-Acridinamine, 6-chloro-2-methoxy-(9CI)
Acridine, 9-amino-6-chloro-2-methoxy-(8CI)
636-858-3
3548-09-2
6-chloro-2-methoxyacridin-9-amine
ACMA
NSC-15300
Bis-t-butyldimethylsilyl 6,6'-Dihydroxypregabalin Lactam
4-(3-((t-Butyldimethylsilyl)oxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)pyrrolidin-2-one
R9EB8YPL49
BIDD:GT0515
CHEMBL76954
SCHEMBL106725
BDBM24710
IHHSSHCBRVYGJX-UHFFFAOYSA-N
EX-A7409
NSC15300
5-Amino-2-chloro-7-methoxyacridine
6-chloro-2-methoxy-acridin-9-amine
6-Chloro-2-methoxyacridine-9-ylamine
AKOS027381471
WLN: T C666 BNJ EG IZ LO1
AS-61900
PD057853
DB-081106
HY-118155
CS-0065321
G-185
NS00115908
D85361
9-Amino-6-chloro-2-methoxyacridine, suitable for fluorescence, >=95%