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6-Chloro-2-phenylbenzimidazole

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Identification
Molecular formula
C13H9ClN2
CAS number
56341-41-4
IUPAC name
6-chloro-2-phenyl-1H-benzimidazole
State
State

At room temperature, 6-Chloro-2-phenylbenzimidazole is in a solid state.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
432.00
Boiling point (Kelvin)
705.15
General information
Molecular weight
240.68g/mol
Molar mass
240.6770g/mol
Density
1.2900g/cm3
Appearence

6-Chloro-2-phenylbenzimidazole appears as a crystalline solid. Its color ranges from off-white to pale yellow, dependent on the specific sample and purity.

Comment on solubility

Solubility of 6-chloro-2-phenyl-1H-benzimidazole

The solubility of 6-chloro-2-phenyl-1H-benzimidazole can be an intriguing topic for researchers and chemists alike. This compound exhibits limited solubility in water, which can be attributed to its relatively nonpolar structure and the presence of chlorine and aromatic groups. Understanding its solubility characteristics is essential for applications in pharmaceuticals and organic synthesis.

Some important points to note regarding the solubility of this compound include:

  • Polar Solvents: It shows enhanced solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) and methanol, making these solvents suitable for dissolution purposes.
  • Temperature Dependency: The solubility can increase with temperature, which is a common behavior observed in many organic compounds.
  • pH Influence: The solubility may be affected by the pH of the solution, especially in acidic or basic conditions where the functional groups may ionize, potentially increasing solubility.

In conclusion, understanding the solubility of 6-chloro-2-phenyl-1H-benzimidazole not only assists in its practical applications but also enriches our knowledge about the interactions of compounds with different solvents. As one saying goes, "Solubility is the gateway to chemistry," highlighting its crucial role in chemical processes and formulations.

Interesting facts

Interesting Facts about 6-Chloro-2-phenyl-1H-benzimidazole

6-Chloro-2-phenyl-1H-benzimidazole is a fascinating compound that has garnered attention in various fields of chemistry and pharmacology. Here are some intriguing points about this compound:

  • Structural Complexity: This organic molecule features a benzimidazole core, which is a fused aromatic ring system. The presence of both a chlorine substituent and a phenyl group makes it particularly interesting for synthetic applications.
  • Biological Activity: Compounds containing benzimidazole moieties often exhibit notable biological activities, including antimicrobial and anticancer properties. Researchers are actively investigating their potential therapeutic effects.
  • Synthesis: The synthesis of 6-chloro-2-phenyl-1H-benzimidazole can involve various methods, including cyclization reactions. This versatility allows chemists to explore different routes and optimize conditions for yield and purity.
  • Applications: Aside from its potential medicinal applications, compounds like this one are often used in the development of dyes, agrochemicals, and materials science.
  • Environmental Considerations: The study of halogenated compounds, such as those containing chlorine, has raised awareness of their environmental impact. Chemists are keen to understand their stability, degradation pathways, and overall ecological footprint.

In summary, 6-chloro-2-phenyl-1H-benzimidazole exemplifies the intersection of organic chemistry, biology, and environmental science. Its diverse potential applications make it a compound worth studying for anyone interested in the vast world of chemical compounds.

Synonyms
4926-65-2
6-chloro-2-phenyl-1H-benzimidazole
5-Chloro-2-phenyl-1H-benzo[d]imidazole
5-Chloro-2-phenyl-1H-benzoimidazole
5-Chloro-2-phenyl-1H-1,3-benzodiazole
5-chloro-2-phenyl-1H-benzimidazole
MFCD00453938
CHEMBL1534413
1H-BENZIMIDAZOLE, 6-CHLORO-2-PHENYL-
5-chloro-2-phenylbenzimidazole
SCHEMBL3335842
SCHEMBL8337597
ALBB-033239
BDBM50417862
STK242093
AKOS003238951
NCGC00142643-01
LS-12557
DB-196497
F15041
SR-01000311126
SR-01000311126-1