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6-Chloroglucose

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Identification
Molecular formula
C6H11ClO6
CAS number
/
IUPAC name
6-chloro-2,3,4,5-tetrahydroxy-hexanal
State
State

At room temperature, 6-Chloroglucose is a solid. Its crystalline form is stable under normal conditions and it remains in the solid state until melting.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
198.56g/mol
Molar mass
198.5580g/mol
Density
2.1000g/cm3
Appearence

6-Chloroglucose is typically a white crystalline solid. Its crystalline structure may vary slightly depending on the purity and specific allotrope. As a chlorinated sugar derivative, it has a characteristic appearance similar to other sugar alcohols.

Comment on solubility

Solubility of 6-Chloro-2,3,4,5-tetrahydroxy-hexanal

The solubility of 6-chloro-2,3,4,5-tetrahydroxy-hexanal can be influenced by various factors such as temperature, pH, and the presence of other solutes. Being a polyhydric compound, it contains multiple hydroxyl (–OH) groups that contribute to its solubility characteristics:

  • Hydrophilicity: The numerous –OH groups enhance the ability of this compound to interact with water, making it relatively soluble in polar solvents.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature; thus, heating may facilitate its dissolution.
  • Presence of Chlorine: The chlorine substituent may introduce some steric hindrance, potentially affecting solubility in various solvents.

In general, compounds with multiple hydroxyl groups are known for their high solubility in water due to the formation of hydrogen bonds. To quote a common principle, “the more hydroxyl groups, the more water-soluble the compound tends to be.” However, the extent of solubility can vary, and empirical testing may be required to determine precise solubility limits in specific solvents.

Understanding the solubility profile of 6-chloro-2,3,4,5-tetrahydroxy-hexanal is crucial for applications in fields such as pharmaceuticals, where solubility can influence bioavailability and absorption.

Interesting facts

Interesting Facts about 6-Chloro-2,3,4,5-tetrahydroxy-hexanal

6-Chloro-2,3,4,5-tetrahydroxy-hexanal is a fascinating compound that plays a noteworthy role in organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structural Complexity: This molecule features a complex structure with multiple hydroxyl groups, which dramatically impacts its reactivity and interactions with biological systems. The presence of chlorine adds another layer of reactivity, making it a valuable building block in synthetic chemistry.
  • Biological Relevance: Compounds with hydroxyl (-OH) groups can significantly influence hydration and solubility, often leading to enhanced biological activity. This particular compound may interact with various enzymes and receptors, highlighting its potential therapeutic applications.
  • Chiral Centers: The compound possesses multiple chiral centers. This chirality opens up avenues for studying enantiomeric forms, which can exhibit vastly different biological activities. The study of these forms is crucial in drug development, where the efficacy and safety of a specific enantiomer are paramount.
  • Synthesis Potential: Chemists are continually exploring new synthetic routes to produce complex organic molecules. The synthesis of 6-chloro-2,3,4,5-tetrahydroxy-hexanal could provide insights into new methodologies, particularly in generating compounds with multiple functional groups.
  • Application in Research: This compound can serve as a lead structure for the development of new drugs or bioactive molecules. Researchers often modify the existing structure to create derivatives with improved properties, making it a cornerstone in medicinal chemistry.

In summary, 6-chloro-2,3,4,5-tetrahydroxy-hexanal is much more than just its chemical structure; it represents a plethora of opportunities in research and applications that continue to intrigue scientists around the world.

Synonyms
6-Chloro-6-deoxymannose
D-Mannose, 6-chloro-6-deoxy-
MANNOSE, 6-CHLORO-6-DEOXY-
4990-81-2
6-chloro-6-deoxy-d-mannose
6-chloro-2,3,4,5-tetrahydroxyhexanal
SCHEMBL11076376
MC08735