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CL 218872

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Identification
Molecular formula
C14H15ClN2O2
CAS number
58753-82-3
IUPAC name
6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one
State
State

At room temperature, 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one is typically a solid. It retains its solid state until it reaches its melting point.

Melting point (Celsius)
98.50
Melting point (Kelvin)
371.65
Boiling point (Celsius)
177.30
Boiling point (Kelvin)
450.45
General information
Molecular weight
279.74g/mol
Molar mass
279.7410g/mol
Density
1.3387g/cm3
Appearence

6-Chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one typically appears as a crystalline solid with a white to off-white color, under ambient conditions. It is a stable compound and should be stored in a cool, dry place.

Comment on solubility

Solubility of 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one

The solubility of 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one can be influenced by various factors, including its molecular structure and interactions with solvents. Here are some key points to consider:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents like water, while hydrophobic regions could favor solubility in organic solvents.
  • Hydrogen bonding: The potential for hydrogen bonding with solvents can significantly affect solubility. Compounds with sites available for hydrogen bonding tend to be more soluble in polar solvents.
  • Temperature: Generally, increasing temperature increases the solubility of solids in liquids, which could potentially apply here.
  • pH dependence: If the compound is ionic or has functional groups that can be protonated or deprotonated, its solubility might vary with pH changes.

It is often stated that "like dissolves like," indicating that the solubility of 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one may be higher in solvents that share similar properties with itself. Understanding these solubility attributes is crucial for applications in drug formulation and chemical synthesis.

Interesting facts

Interesting Facts about 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one

This intriguing compound, known as 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one, belongs to a class of chemicals that display significant biological activity, particularly in pharmacology. Its unique structural characteristics allow it to interact with various biological systems, making it a subject of interest in medicinal chemistry.

Key Features of the Compound:

  • Piperidine Ring: The presence of a piperidine moiety enhances the compound’s affinity for biological targets, particularly in neurological studies.
  • Benzoxazol Structure: The benzoxazole component contributes to its potential as a drug candidate, with implications in treating various conditions.
  • Chlorine Substitution: The chlorine atom plays a crucial role in modulating the compound's reactivity and bioavailability.

Research has indicated that compounds with similar frameworks can exhibit a range of activities, including:

  1. Antidepressant effects
  2. Antinociceptive properties
  3. Anticancer potential

Moreover, scientists are particularly fascinated by the possibility of optimizing this compound to enhance its efficacy while reducing side effects. As noted in the words of famous chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This notion resonates well with researchers exploring the potential of benzoxazole derivatives.

With ongoing studies in synthetic modifications and biological evaluations, the exploration of 6-chloro-3-[2-(1-piperidyl)ethyl]-1,3-benzoxazol-2-one continues to unfold new possibilities in the realm of pharmaceutical development.