Skip to main content

Clozapine N-oxide hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C18H19ClN3O
CAS number
34233-66-4
IUPAC name
6-chloro-3-(2-pyridin-1-ium-4-ylethyl)-1,4-dihydro-2,3-benzoxazine;chloride
State
State

At room temperature, Clozapine N-oxide hydrochloride is typically in a solid state. It is non-volatile and stable under normal conditions of use and storage.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
342.17g/mol
Molar mass
342.1670g/mol
Density
1.4000g/cm3
Appearence

Clozapine N-oxide hydrochloride typically appears as a solid crystalline powder. The color can range from white to off-white or slightly yellowish, depending on purity and storage conditions. It is often used in a laboratory setting for various experimental applications.

Comment on solubility

Solubility of 6-chloro-3-(2-pyridin-1-ium-4-ylethyl)-1,4-dihydro-2,3-benzoxazine; chloride

The solubility characteristics of 6-chloro-3-(2-pyridin-1-ium-4-ylethyl)-1,4-dihydro-2,3-benzoxazine; chloride can be quite intricate due to its unique structure. This compound contains both hydrophobic (non-polar) and hydrophilic (polar) regions, which can influence its behavior in various solvents.

Factors Influencing Solubility

  • Ionic Nature: The presence of a chloride ion suggests that the compound may exhibit increased solubility in polar solvents, such as water.
  • Presence of Pyridine: The pyridinium moiety enhances its solubility in organic solvents due to its polar character.
  • Hydrophobic Benzoxazine Ring: The benzoxazine portion may create a propensity for the compound to be more soluble in organic solvents.

In summary, 6-chloro-3-(2-pyridin-1-ium-4-ylethyl)-1,4-dihydro-2,3-benzoxazine; chloride demonstrates intriguing solubility dynamics, where it is expected to be soluble in both polar and non-polar solvents to varying degrees. Experimentation is necessary to ascertain its solubility in specific solvents, making it essential for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 6-Chloro-3-(2-Pyridin-1-ium-4-ylethyl)-1,4-Dihydro-2,3-Benzoxazine; Chloride

This unique compound, with its multifaceted structure, embodies the intersection of organic synthesis and medicinal chemistry. Here are some fascinating insights:

  • Complex Structure: The compound features a benzoxazine core, which is known for its potential in *pharmaceutical applications* due to its diverse reactivity and biological activity.
  • Pyridine Component: The inclusion of a pyridine moiety enhances the compound's *bioactivity*, making it a candidate for various therapeutic applications, particularly in the field of antimicrobials and anticancer agents.
  • Chlorine Atom: The presence of the chlorine atom contributes to the compound's *electronic properties*, which can influence how it interacts with biological targets. Chlorinated compounds often exhibit enhanced potency compared to their non-chlorinated counterparts.
  • Salt Formation: The chloride salt form of this compound is significant for *solubility and stability*, which are essential for pharmaceutical formulations. It allows for better absorption in biological systems.
  • Research Potential: The structural features of this compound provide a rich platform for *modification*. Chemists are often interested in derivatives that could lead to *improved efficacy or reduced toxicity*.

As research progresses, compounds like this serve as vital tools in the quest for new *medications* and *therapeutics*. The field of medicinal chemistry constantly seeks innovative compounds, and the unique characteristics of 6-chloro-3-(2-pyridin-1-ium-4-ylethyl)-1,4-dihydro-2,3-benzoxazine; chloride highlight just how intricate and promising chemical research can be.


"In every molecule lies the potential for a remedy." – Anonymous

Synonyms
1H-2,3-BENZOXAZINE, 3,4-DIHYDRO-6-CHLORO-3-(2-(4-PYRIDYL)ETHYL)-, HYDROCHLORIDE
26694-00-8
6-Chloro-3-(2-(4-pyridyl)ethyl)-3,4-dihydro-1H-2,3-benzoxazine
1H-2,3-Benzoxazine, 6-chloro-3,4-dihydro-3-(2-(4-pyridyl)ethyl)-, hydrochloride
RefChem:237276