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6-chloro-3,4-dihydro-2H-1,4-benzoxazine

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Identification
Molecular formula
C8H8ClNO
CAS number
136310-09-5
IUPAC name
6-chloro-3,4-dihydro-1H-2,3-benzoxazine
State
State

This compound typically exists in a solid state at room temperature.

Melting point (Celsius)
84.50
Melting point (Kelvin)
357.70
Boiling point (Celsius)
315.40
Boiling point (Kelvin)
588.50
General information
Molecular weight
185.61g/mol
Molar mass
185.6200g/mol
Density
1.3763g/cm3
Appearence

6-Chloro-3,4-dihydro-2H-1,4-benzoxazine typically appears as a crystalline solid with a white to off-white coloration. The compound may be available in a powdery form with a smooth texture.

Comment on solubility

Solubility of 6-chloro-3,4-dihydro-1H-2,3-benzoxazine

6-chloro-3,4-dihydro-1H-2,3-benzoxazine displays interesting solubility characteristics that can be clarified through several factors:

  • Solvent Compatibility: This compound is generally soluble in organic solvents, reflecting its lipophilic nature.
  • Polarity Considerations: The presence of the chlorine atom introduces some polarity, potentially enhancing its solubility in polar organic solvents.
  • Hydrogen Bonding: The benzoxazine structure can engage in hydrogen bonding, which may affect solubility in water, suggesting limited solubility in this polar solvent.
  • Temperature Influence: Like many organic compounds, solubility may increase with temperature, although specific data on this compound may vary.

In summary, while 6-chloro-3,4-dihydro-1H-2,3-benzoxazine may not be highly soluble in water, it demonstrates greater solubility in various organic solvents, making it suitable for applications in organic synthesis and material science. Always consider the specific conditions and solvents used for dissolution to achieve optimal results.

Interesting facts

Interesting Facts About 6-chloro-3,4-dihydro-1H-2,3-benzoxazine

6-chloro-3,4-dihydro-1H-2,3-benzoxazine is an intriguing chemical compound that combines features of both heterocycles and chlorinated structures. Here are some fascinating insights into this compound:

  • Heterocyclic Chemistry: This compound belongs to the benzoxazine family, which are known for their unique properties as heterocycles containing both oxygen and nitrogen atoms.
  • Pharmaceutical Relevance: Compounds like 6-chloro-3,4-dihydro-1H-2,3-benzoxazine are often studied for their potential uses in pharmaceuticals, particularly in the development of drugs that can target specific biological pathways.
  • Mechanism of Action: Research suggests that such compounds might exhibit various biological activities, including anti-inflammatory and antibacterial effects, making them valuable in medicinal chemistry.
  • Structural Versatility: The presence of chlorine in this compound enhances its structural diversity and reactivity, which can lead to the development of new derivatives with altered properties.
  • Research Applications: As scientists continue to explore the properties and applications of benzoxazines, 6-chloro-3,4-dihydro-1H-2,3-benzoxazine may offer insights into designing novel materials for various industrial uses.

In summary, the study of 6-chloro-3,4-dihydro-1H-2,3-benzoxazine not only contributes to our understanding of heterocyclic compounds but also holds potential for advancing medicinal chemistry. Its unique structure and possible biological activities open the door for further exploration and innovation.

Synonyms
6-Chloro-3,4-dihydro-1H-2,3-benzoxazine
21977-33-3
BRN 1103559
1H-2,3-BENZOXAZINE, 3,4-DIHYDRO-6-CHLORO-
1H-2,3-Benzoxazine, 6-chloro-3,4-dihydro-
DTXSID70176387
RefChem:237275
DTXCID7098878