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nuciferine

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Identification
Molecular formula
C19H14ClNO2
CAS number
475-83-2
IUPAC name
6-chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
State
State

At room temperature, nuciferine exists as a solid.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
295.78g/mol
Molar mass
295.7370g/mol
Density
1.3150g/cm3
Appearence

Nuciferine appears as a yellowish-brown, amorphous powder. It may have a slight crystallinity depending on the degree of purification.

Comment on solubility

Solubility of 6-chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one

The solubility of 6-chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one (C19H14ClNO2) in various solvents exhibits noteworthy characteristics influenced by its molecular structure. Generally, the solubility can be considered based on the following factors:

  • Polarity: The presence of chlorine and hydroxyl groups introduces polar characteristics, making the compound potentially soluble in polar solvents like water or methanol, but it may exhibit limited solubility.
  • Aromatic Characteristics: With significant aromatic rings, the compound's hydrophobic nature can lead to greater solubility in organic solvents such as ethyl acetate and dichloromethane.
  • Temperature Dependence: Solubility may increase with temperature, indicating that higher temperatures could favor dissolution in certain solvents.

In studies, it’s often observed that the solubility of such organic compounds is governed by their specific interactions with solvent molecules, leading to varied results depending on the chosen medium. Hence, it is paramount to conduct detailed solubility tests to confirm the solubility profile across different solvents.

As quoted in solubility studies, “the pathway to solubility can reveal hidden potential in compounds,” underlining the importance of thorough investigation in the development and application of such chemical entities.

Interesting facts

Interesting Facts About 6-Chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one

This fascinating compound is a member of the class of chemical compounds known as quinolines, which are notable for their diverse biological activities. Here are some interesting insights about 6-chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one:

  • Medicinal Potential: Compounds like this one are of great interest in medicinal chemistry due to their potential therapeutic properties. Studies have indicated that derivatives of this structure can exhibit antibacterial and anticancer activities.
  • Complex Structure: The compound has a complex bicyclic structure that facilitates various chemical reactions, making it a versatile substrate in organic synthesis.
  • Synthetic Pathways: The synthesis of this compound can involve various organic reactions, showcasing the creativity and ingenuity required in synthetic organic chemistry.
  • Research Applications: Researchers employ this compound as a basis for developing new drugs, leveraging its unique properties to synthesize analogs that may demonstrate improved efficacy or reduced side effects.
  • Chlorine Atom Influence: The presence of a chlorine atom in its structure often enhances biological activity and allows for manipulation during chemical reactions, making it an attractive subject for synthetic chemists.

As highlighted by the famous chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." In the field of chemical compounds, each structure opens doors to a myriad of potential applications and discoveries. The study of compounds like 6-chloro-3a-hydroxy-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one exemplifies this sentiment, serving as a reminder of the endless possibilities in chemical research.

Synonyms
Bio1_000828
CBiol_002053
SCHEMBL23909198
Bio1_000339
Bio1_001317