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6-Chloro-2-benzoxazolinone

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Identification
Molecular formula
C7H4ClNO2
CAS number
1771-18-2
IUPAC name
6-chloro-3H-1,3-benzoxazol-2-one
State
State

At room temperature, 6-Chloro-2-benzoxazolinone is typically found in a solid state, taking the form of crystalline powder mentioned in the appearance section.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
327.10
Boiling point (Kelvin)
600.25
General information
Molecular weight
169.57g/mol
Molar mass
169.5680g/mol
Density
1.4160g/cm3
Appearence

6-Chloro-2-benzoxazolinone typically appears as a white to off-white crystalline powder. The compound is characterized by its fine crystals, which may have a slightly granular texture. It is known for its chemical stability and is often used in various chemical synthesis applications.

Comment on solubility

Solubility of 6-Chloro-3H-1,3-benzoxazol-2-one

The solubility of 6-chloro-3H-1,3-benzoxazol-2-one in various solvents offers insights into its chemical behavior and potential applications. This compound is generally characterized by:

  • Limited solubility in water: Typically, aromatic compounds such as this one exhibit low solubility due to their non-polar characteristics.
  • Better solubility in organic solvents: It tends to dissolve more readily in organic solvents, including:
    • Dimethyl sulfoxide (DMSO)
    • Acetone
    • Ethyl acetate
    • Methanol
    • Chloroform

When discussing solubility, it is essential to remember that:

  • Temperature: Higher temperatures often enhance solubility, making it more versatile in various experimental conditions.
  • pH Factors: In more acidic or alkaline conditions, the solubility may change due to protonation or deprotonation of functional groups.

In conclusion, understanding the solubility of 6-chloro-3H-1,3-benzoxazol-2-one is crucial for pharmaceutical and chemical studies, allowing researchers to predict its behavior in different environments.

Interesting facts

Interesting Facts about 6-Chloro-3H-1,3-benzoxazol-2-one

6-Chloro-3H-1,3-benzoxazol-2-one is a fascinating compound that resides in the realm of heterocyclic chemistry. This compound is known for its unique structure and potential applications, making it an interesting subject for chemists and researchers alike.

Key Features

  • Heterocyclic Structure: It belongs to the benzoxazole family, characterized by a fusion of a benzene ring and an oxazole ring, which provides it with distinct chemical properties.
  • Chlorination: The presence of a chlorine atom enhances its reactivity and may influence its biological activities.
  • Biological Activity: Compounds of this class have been studied for their potential antimicrobial, anti-inflammatory, and antitumor properties, making them significant in medicinal chemistry.

Applications

This compound is worthy of attention in various fields, such as:

  • Pharmaceutical Development: Researchers are exploring its potential in drug formulation aimed at treating various conditions.
  • Analytical Chemistry: Its unique structure may serve as a reference compound for developing analytical methods.
  • Material Science: The compound could also find utility in synthesizing novel materials with specialized properties.

Quote to Inspire

As the renowned chemist Robert H. Grubbs once said, “When one has a great deal of scientific knowledge, one has to put it to good use.” The ongoing exploration of compounds like 6-chloro-3H-1,3-benzoxazol-2-one exemplifies the pursuit of innovation shaping the future of science.

This compound serves as a reminder of the intricate connections between structure and function in chemistry. Its development and application could pave the way for new discoveries and advancements across various scientific disciplines.

Synonyms
19932-84-4
6-Chloro-2-benzoxazolinone
2(3H)-Benzoxazolone, 6-chloro-
6-Chlorobenzoxazolone
6-Chloro-2,3-dihydrobenzoxazol-2-one
PG1JLE50LE
DTXSID2041545
NSC-26191
DTXCID0021545
CDHB cpd
634-962-3
RefChem:104373
6-Chloro-1,3-benzoxazol-2(3H)-one
6-Chlorobenzo[d]oxazol-2(3H)-one
6-Chlorobenzoxazolinone
6-chloro-3H-1,3-benzoxazol-2-one
6-Chloro-2-benzoxazolone
6-Chlorobenzoxazol-2(3H)-one
2-BENZOXAZOLINONE, 6-CHLORO-
HOE 54014
MFCD00463914
6-chloro-2,3-dihydro-1,3-benzoxazol-2-one
6-chloro-3-hydrobenzoxazol-2-one
NSC664284
6-Chloro-3H-benzooxazol-2-one
2(3H)-Benzoxazolone,6-chloro-
UNII-PG1JLE50LE
NSC 26191
BRN 0135505
NSC26191
6-chlorobenzoxazolin-2-one
6-Chloro-2-hydroxybenzoxazole
6-Chlorobenzo[d]oxazol-2-ol
SCHEMBL1519891
SCHEMBL5540298
SCHEMBL9252784
SCHEMBL9252792
CHEMBL1989517
SCHEMBL11203900
ALBB-012646
Tox21_301408
CCG-54863
SBB003865
STK366147
AKOS000511153
AKOS006241610
AE F054014
NSC-664284
NCGC00255552-01
6-Chloro-1,3-benzoxazol-2(3H)-one #
AC-27541
BP-10117
NCI60_022159
ST018509
CAS-19932-84-4
DB-015142
DB-197089
6-Chloro-3h-benzooxazol-2-one; sodium salt
C2378
CS-0188218
NS00021051
EN300-14213
D89508
SR-01000643926-1
Q27286528
Z99599674
6-Chlorobenzoxazol-2(3H)-one, PESTANAL(R), analytical standard