Interesting facts
Interesting Facts about 6-Chloro-4-(2-Cyclopropylethynyl)-4-(Trifluoromethyl)-1H-3,1-Benzoxazin-2-one
This compound is a fascinating example of modern synthetic chemistry, combining unique structural and functional features that hold potential in various applications. Here are some intriguing insights:
- Structural Diversity: The presence of both a chloro group and a trifluoromethyl group enhances the compound's electronic properties and reactivity, making it a prime candidate for further derivatization in drug design.
- Cyclopropyl Moiety: The incorporation of a cyclopropyl group is noteworthy. Cyclopropyl rings can impart strain and unique steric effects, influencing biological activity and leading to compounds with enhanced pharmacological profiles.
- Benzoxazinone Framework: The benzoxazinone structure is recognized for its role in various bioactive compounds, often associated with anti-tumor and anti-inflammatory activities. This suggests potential therapeutic implications for the synthesized compound.
- Fluorine’s Influence: The trifluoromethyl group not only affects lipophilicity but also helps in modulating the compound's metabolic stability, an important consideration in drug development.
- Bioactivity Potential: Compounds with such intricate architectures have been studied for their activity against certain cancer cell lines, highlighting their importance in medicinal chemistry research.
As a result of its complex design, 6-Chloro-4-(2-Cyclopropylethynyl)-4-(Trifluoromethyl)-1H-3,1-Benzoxazin-2-one exemplifies how structural modifications can lead to enhanced functional properties. This compound is not only of academic interest but also poses promising avenues for therapeutic innovations.
Synonyms
Rac-Efavirenz
177530-93-7
L 741211
6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
154635-17-3
rac Efavirenz
6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Efavirenz Racemic
(Rac)-Efavirenz
rac Efavirenz-d4
6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one
6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
SMR000718784
L-741211
Racemic-Efavirenz
NCGC00159337-02
1246812-58-7
Efavirenz Racemic; ((+/-)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one)
(+/-)-Efavirenz
1261394-62-0
Efavirenz Racemic (20mg)
6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
L741211
MLS001304019
MLS006011825
CHEMBL59507
SCHEMBL464769
DTXSID00861416
HMS2231D09
HMS3373J19
HVB64295
WZB81258
Tox21 111582
BBL010771
HY-10572B
STK582240
STL454184
AKOS005506207
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-
6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-3-one
NCGC00159337-03
NCGC00159337-06
FC100188
SY009682
VS-02672
CS-0092492
AB00876268-06
(+) 6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl- 1,4-dihydro-2H-3,1-benzoxazin-2-one
(+) 6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
(+/-) 6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
(+/-)6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-4H-3,1-benzoxazin-2-ol
(S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
Solubility of 6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
The solubility of chemical compounds is a key characteristic that influences their behavior and application in various fields. In the case of 6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one (C23H11ClF3N3O2), understanding its solubility properties can provide insights into its potential uses and efficacy.
Factors Affecting Solubility
Several factors typically influence the solubility of compounds like this one:
Potential Solubility
While specific solubility data for this compound may not be readily available, it is reasonable to hypothesize:
In summary, the solubility of 6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one plays a crucial role in its usability across different domains, and understanding these characteristics can greatly assist in its practical application.