Skip to main content

Clorotepine acetate

ADVERTISEMENT
Identification
Molecular formula
C21H15ClN4O5S
CAS number
10556-72-4
IUPAC name
6-chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide
State
State

At room temperature, Clorotepine acetate is in a solid state, typically forming a crystalline powder.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
476.00
Boiling point (Kelvin)
749.15
General information
Molecular weight
433.88g/mol
Molar mass
433.8790g/mol
Density
1.4000g/cm3
Appearence

Clorotepine acetate appears as a pale yellow solid which is crystalline in nature. It typically forms a fine powder and can be visually identified by its distinct color.

Comment on solubility

Solubility of 6-chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide

The solubility of the compound 6-chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide can be influenced by its complex structure. Here are some key aspects that shed light on its solubility characteristics:

  • Polarity: The presence of polar functional groups such as carboxamide and sulfamoyl may increase solubility in polar solvents like water.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding, enhancing its interactions with solvent molecules; thus, it may exhibit better solubility in polar solvents.
  • Aromaticity: The aromatic rings can contribute to solubility in organic solvents, indicating it may have variable solubility depending on the solvent system used.
  • Temperature: Solubility can be temperature-dependent; typically, increasing temperature may improve solubility due to increased molecular movement.
  • pH Dependency: As a compound containing both acidic and basic functional groups, its solubility might change with pH, offering different profiles in acidic versus basic environments.

In summary, while this compound exhibits a potential for solubility in both aqueous and organic media, the specific solubility profile would require experimental determination to ascertain its behavior under various conditions. As a general observation, compounds with similar architectures tend to be moderately soluble in polar solvents yet show varied results in nonpolar environments. It is essential to conduct thorough solubility testing to understand its practical applications fully.

Interesting facts

Interesting Facts about 6-Chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide

6-Chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide is a fascinating compound that belongs to a class of organic molecules with unique properties and applications. Here are some intriguing insights:

  • Pharmaceutical Potential: This compound has garnered interest in medicinal chemistry due to its structural features, which may provide insights into the design of new pharmaceuticals.
  • Structural Diversity: The combination of the chromene moiety with sulfamoyl and pyrimidine groups contributes to its potential to interact with biological targets in diverse ways.
  • Synthesis Pathways: The synthesis of such complex compounds often involves multiple reaction steps, showcasing the creativity and innovation required in synthetic organic chemistry.
  • Biological Activity: Research into sulfonamide derivatives, to which this compound is related, suggests potential antibacterial and antitumor activities, making it a promising candidate for further studies.
  • Mechanistic Insights: Understanding how this compound interacts at the molecular level with biological systems can provide insights into its efficacy and safety profile as a therapeutic agent.

In conclusion, 6-chloro-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]-4-oxo-chromene-2-carboxamide epitomizes the intricate relationship between chemical structure and biological activity. As a student or scientist delving into the realm of organic compounds, this molecule serves as an excellent example of the innovative strategies employed in drug discovery.

Synonyms
BRN 0949209
4H-1-Benzopyran-2-carboxanilide, 6-chloro-4'-(4-methyl-2-pyrimidinylsulfamoyl)-4-oxo-
27455-37-4
DTXSID90181872
6-Chloro-4'-(4-methyl-2-pyrimidinylsulfamoyl)-4-oxo-4H-1-benzopyran-2-carboxanilide
RefChem:297185
DTXCID30104363