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6-Chlorocoumarin

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Identification
Molecular formula
C9H5ClO2
CAS number
1885-14-9
IUPAC name
6-chlorochromen-2-one
State
State
This compound is usually found in a solid state at room temperature with a pale yellow color.
Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
324.00
Boiling point (Kelvin)
597.15
General information
Molecular weight
180.59g/mol
Molar mass
180.5880g/mol
Density
1.4100g/cm3
Appearence
6-Chlorocoumarin is typically seen as a pale yellow crystalline solid.
Comment on solubility

Solubility of 6-chlorochromen-2-one

6-chlorochromen-2-one, a compound belonging to the class of flavonoids, typically exhibits moderate solubility in various solvents. The solubility characteristics can vary depending on several factors:

  • Polarity: Due to its aromatic structure and chlorine substitution, this compound is more soluble in polar organic solvents like ethanol and methanol.
  • Temperature: Increasing temperature often enhances solubility, allowing for better dissolution in solvents.
  • pH Level: The solubility of 6-chlorochromen-2-one can also be affected by the pH of the solution, with changes potentially impacting its ionization state.

In water, 6-chlorochromen-2-one demonstrates limited solubility, which is common for many aromatic compounds due to their hydrophobic nature. As such, it is more likely to dissolve in organic solvents than in aqueous solutions.

In summary, while 6-chlorochromen-2-one does exhibit some solubility in organic solvents, its behavior in water is largely governed by its structural characteristics and environmental conditions.

Interesting facts

Interesting Facts about 6-Chlorochromen-2-one

6-Chlorochromen-2-one, also known as 6-Chloroflavone, is a fascinating compound with numerous intriguing characteristics worthy of exploration.

Chemical Structure and Properties

Belonging to the flavonoid family, this compound exhibits a unique:

  • Bicyclic structure - The combination of the chromenone and chlorinated moieties contributes to its chemical reactivity.
  • Presence of a chlorine atom - This substitution can enhance biological activity and influence the compound's interaction with enzymes, making it a point of interest in pharmacology.

Biological Significance

6-Chlorochromen-2-one has garnered attention in various fields due to its potential therapeutic applications:

  • Antioxidant Activity - Like many flavonoids, it may contribute to scavenging free radicals, thus supporting cellular health.
  • Anti-inflammatory Properties - Early studies indicate a potential role in reducing inflammation, making it a candidate for new therapeutic strategies.
  • Cancer Research - Some research suggests that it may have anticancer effects, triggering apoptosis in certain types of cancer cells.

Applications in Research

Researchers are continuously exploring the multifaceted nature of this compound:

  • Natural Products Chemistry - 6-Chlorochromen-2-one is often investigated as a lead compound for the synthesis of more complex molecules.
  • Drug Development - It serves as a promising scaffold for designing new pharmaceuticals targeting various diseases.

Quote to Ponder

As the famous chemist Marie Curie once said, "Nothing in life is to be feared, it is only to be understood." The study of compounds like 6-Chlorochromen-2-one enables us to deepen our understanding of the molecular world.

The exploration of 6-Chlorochromen-2-one represents just a small part of a vast field, with potential implications in scientific innovation and medicine. As research advances, this compound may unveil even more captivating secrets about its role in health and disease.

Synonyms
6-Chlorocoumarin
2H-1-Benzopyran-2-one, 6-chloro-
COUMARIN, 6-CHLORO-
6-Chloro-2H-1-benzopyran-2-one
AI3-03685
BRN 0128035
NSC 4140
DTXSID30870930
5-17-10-00146 (Beilstein Handbook Reference)
DTXCID90818611
2H-1-Benzopyran-2-one, 6-chloro-(9CI)
amqsyjckxpuedr-uhfffaoysa-n
6-chloro-2H-chromen-2-one
2051-59-4
6-chlorochromen-2-one
6-Chloro-chromen-2-one
NSC4140
MFCD01327472
NSC-4140
WLN: T66 BOVJ HG
SCHEMBL3086551
AC5388
AKOS027256911
246B637U2Z
SB35201
BS-15908
DA-36326
SY036153
CS-0145276
AG-205/12008006
SR-01000523045
SR-01000523045-1