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Rocuronium bromide

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Identification
Molecular formula
C32H53ClN2O4
CAS number
119302-91-9
IUPAC name
6-chlorohexyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride
State
State

At room temperature, rocuronium bromide is often stored in a solid state as a powder. It is used in clinical settings usually in its aqueous form for intravenous injection.

Melting point (Celsius)
130.50
Melting point (Kelvin)
403.70
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
610.80g/mol
Molar mass
610.8000g/mol
Density
1.0480g/cm3
Appearence

Rocuronium bromide is typically found as a white or off-white powder. It is known to be hygroscopic, which means it can absorb moisture from the air. When prepared as a solution for injection, it is clear and colorless to slightly yellow.

Comment on solubility

Solubility of 6-chlorohexyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride

The solubility of 6-chlorohexyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride is influenced by its unique structure, which contains both hydrophobic and hydrophilic components. This dual nature affects how well it dissolves in various solvents.

Key Factors Affecting Solubility

  • Polar and Non-Polar Interactions: The presence of the long alkyl chain enhances lipophilicity, contributing to solubility in organic solvents, while the quaternary ammonium group promotes solubility in aqueous solutions.
  • Temperature: Increased temperatures generally promote greater solubility for ionic compounds like this one, specifically in water.
  • pH of the Solution: The solubility may vary with the pH level due to the nature of ionic compounds and their interactions with other ions present in the solution.

Overall, it is reasonable to expect that this compound might show good solubility in polar solvents such as water, thanks to its ionic chloride component, while potentially having lower solubility in non-polar solvents.
"Like dissolves like" aptly describes this phenomenon, where the hydrophobic regions of the molecule align better with non-polar solvents, while the hydrophilic parts interact favorably with polar solvents.

In conclusion, the solubility behavior of this compound can vary significantly based on environmental conditions and solvent choice, making it an intriguing subject for further study.

Interesting facts

Interesting Facts About 6-Chlorohexyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium Chloride

This compound is a fascinating example of quaternary ammonium salts, which have important applications in various fields, including pharmaceuticals, biochemistry, and materials science. Here are some highlights about this intriguing compound:

  • Pharmaceutical Potential: Compounds like this one often display significant biological activity, making them valuable candidates in drug development.
  • Surface Activity: Many quaternary ammonium compounds are surfactants, which help lower surface tension in liquids. This property is essential in formulations like detergents and emulsifiers.
  • Antimicrobial Properties: Quaternary ammonium compounds are known for their disinfectant abilities, and this particular compound may share similar traits, making it useful in cleaning agents and sanitizers.
  • Structural Complexity: The presence of a chlorinated alkyl chain combined with a dimethylanilino moiety illustrates the compound's potential for various interactions at the molecular level, leading to unique chemical behaviors.
  • Research Opportunities: As a chemist, studying this compound can lead to new insights into the structure-activity relationship, facilitating advancements in both medicinal chemistry and organic synthesis.

In the words of a great scientist: "The beauty of chemistry lies in its ability to forge unexpected connections between seemingly unrelated compounds." This can certainly be said for 6-chlorohexyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium chloride, as its structural attributes suggest a multifaceted role in both academic research and practical applications.

Synonyms
25027-87-6
Acetamide, 2-((6-chlorohexyl)methylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride
RefChem:1075203
2-((6-Chlorohexyl)methylamino)-2',6'-acetoxylidide hydrochloride
2',6'-ACETOXYLIDIDE, 2-((6-CHLOROHEXYL)METHYLAMINO)-, MONOHYDROCHLORIDE