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Deferiprone

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Identification
Molecular formula
C14H19NO2
CAS number
30652-11-0
IUPAC name
6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one
State
State

At room temperature, Deferiprone is a solid compound.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.00
Boiling point (Celsius)
579.20
Boiling point (Kelvin)
852.30
General information
Molecular weight
209.31g/mol
Molar mass
209.2670g/mol
Density
1.2840g/cm3
Appearence

Deferiprone appears as a white to off-white powder that is slightly hygroscopic. When pure, it is crystalline in nature.

Comment on solubility

Solubility of 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one

The compound 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one (C14H19NO2) displays interesting solubility characteristics that are primarily influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polar and non-polar interactions: The presence of both a hydroxyl group and a cyclohexyl group in its structure suggests it may exhibit a balance between polar and non-polar interactions.
  • Solubility in solvents: It is likely to be soluble in polar solvents such as water and alcohols due to the hydrophilic nature of the hydroxyl (-OH) group.
  • Possible limitations: However, the bulky cyclohexyl group may hinder complete solubility in more polar solvents, potentially resulting in limited solubility in water.
  • Organic solvents: The compound may show better solubility in organic solvents like methanol, ethanol, and dichloromethane where the non-polar regions of the molecule can interact favorably with the solvent.

In essence, the solubility of 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one can be summarized as a complex interaction between its structural features, showcasing both hydrophilic and hydrophobic characteristics that inform its behavior in various solvent systems.

Interesting facts

Exploring 6-Cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one

6-Cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one is a fascinating compound that captures the interest of chemists and researchers alike due to its unique structure and potential applications. Here are some interesting aspects of this intriguing compound:

  • Versatile Functionality: This compound features a pyridinone structure, which is significant in medicinal chemistry and can lead to various biological activities.
  • Potential Biological Activity: Pyridinones are often investigated for their pharmacological properties, including antioxidant and anti-inflammatory effects, making this compound a candidate for further biological studies.
  • Cyclohexyl Group Impact: The incorporation of a cyclohexyl group influences the compound's hydrophobicity and could potentially enhance its ability to interact with biological membranes.
  • Synthesis Routes: Synthesizing this compound can involve various methods, including multi-step reactions that highlight the versatility of organic synthesis techniques.
  • Applications in Drug Development: Owing to its unique features, compounds like 6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one are explored in the design of new drugs with improved efficacy and reduced side effects.
  • Research Interest: The compound has gained attention for its role in developing therapies targeting diseases where pyridinone derivatives show promise.

In Conclusion: 6-Cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one stands out as a compound that bridges the gap between organic chemistry and medicinal applications. Its unique structural attributes open doors to potential therapeutic advances, making it an exciting topic of study within the chemical community.

Synonyms
CICLOPIROX
29342-05-0
Loprox
Penlac
HOE 296b
cyclopirox
Ciclopiroxum
2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl-
Terit
HOE-296b
Ciclopirox gel
Loprox cream
Ciclopiroxum [INN-Latin]
Loprox Gel
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
Ciclodan
CNL8
EINECS 249-577-2
UNII-19W019ZDRJ
Ciclopirox (Penlac)
19W019ZDRJ
CHEBI:453011
Loprox (TN)
HOE296b
2(1H)-Pyridone, 6-cyclohexyl-1-hydroxy-4-methyl-
DTXSID9048564
Ciclopirox [USAN:USP:INN:BAN]
29342-05-0 (free)
Stieprox
Ciclopiroxum (INN-Latin)
Ciclopirox Olamin
Ciclopirox-Olamin
CICLOPIROX (MART.)
CICLOPIROX [MART.]
CICLOPIROX (USP-RS)
CICLOPIROX [USP-RS]
6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one
CICLOPIROX (EP MONOGRAPH)
CICLOPIROX [EP MONOGRAPH]
CICLOPIROX (USP MONOGRAPH)
CICLOPIROX [USP MONOGRAPH]
Ciclopirox (USAN:USP:INN:BAN)
MLS002153867
Penlac (TN)
Ciclopirox (USP/INN)
SMR001233223
Ciclopirox; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
MFCD00599441
Ciclopirox (Standard)
CICLOPIROX [MI]
CICLOPIROX [INN]
Prestwick0_000541
Prestwick1_000541
Prestwick2_000541
Prestwick3_000541
Spectrum2_000146
Spectrum3_000351
Spectrum4_000288
Spectrum5_000747
CICLOPIROX [USAN]
CICLOPIROX [VANDF]
6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one
CHEMBL1413
CICLOPIROX [WHO-DD]
SCHEMBL34424
BSPBio_000581
BSPBio_002041
KBioGR_000816
6-Cyclohexyl-1-hydroxy-4-methyl-2-(1H)-pyridone
cid_38911
BIDD:GT0080
(6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone)
SPBio_000252
SPBio_002502
BPBio1_000641
CICLOPIROX [ORANGE BOOK]
Ciclopirox, >=98% (HPLC)
DTXCID2028193
BDBM66087
GTPL11349
HY-B0450R
KBio3_001261
6-CYCLOHEXYL-1-HYDROXY-4-METHYL-1H-PYRIDIN-2-ONE
D01AE14
G01AX12
GLXC-10499
HMS3656I12
BCP28530
HY-B0450
s2528
AKOS015895717
AB06517
CCG-266632
DB01188
FC20430
KS-5085
NCGC00017112-04
NCGC00017112-05
NCGC00017112-06
NCGC00017112-08
NCGC00017112-11
NCGC00178850-01
NCGC00178850-02
AC-24195
SBI-0206690.P002
DB-047566
HOE 296; HOE-296;Ciclopiroxum; Penlac
1-hydroxy-4-methyl-6-cyclohexyl-2-pyridone
NS00010120
SW196923-5
D03488
EN300-197928
AB00053438_09
AB00053438_10
AB00053438_11
Q419468
SR-05000001589-5
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone #
BRD-K13044802-001-02-4
BRD-K13044802-001-03-2
BRD-K13044802-213-04-1
BRD-K13044802-213-09-0
BRD-K13044802-213-20-7
BRD-K13044802-213-21-5
BRD-K13044802-213-24-9
BRD-K13044802-213-25-6
Z1509504366
2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methyl-2-pyridone
Ciclopirox, European Pharmacopoeia (EP) Reference Standard
2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methyl-2-pyridinone
2-azanylethanol;6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one
Ciclopirox, United States Pharmacopeia (USP) Reference Standard
249-577-2