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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
6-(dimethylamino)-4,4-diphenyl-heptan-3-one
State
State

At room temperature, methadone is generally encountered in either a crystalline or a liquid form depending on its formulation for use. As a pure compound, it exists in solid state but for medical purposes, it is often diluted in liquid solutions.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
215.50
Boiling point (Kelvin)
488.65
General information
Molecular weight
309.45g/mol
Molar mass
309.4510g/mol
Density
0.9000g/cm3
Appearence

Methadone is typically available as a white to off-white crystalline powder. It can also be found in liquid form, often as a clear, colorless solution when used for medical applications. It may sometimes appear as tablet formulations or pre-measured liquid bottles.

Comment on solubility

Solubility of 6-(dimethylamino)-4,4-diphenyl-heptan-3-one

The solubility of 6-(dimethylamino)-4,4-diphenyl-heptan-3-one (C21H27NO) can be influenced by several factors, making it an interesting compound to study. Here are some key considerations regarding its solubility:

  • Polarity: The presence of the dimethylamino group enhances the polarity of this compound, which can contribute to its solubility in polar solvents, such as water.
  • Hydrophobic characteristics: With a large hydrocarbon framework and two phenyl groups, the compound exhibits significant hydrophobic properties, potentially limiting its solubility in highly polar solvents.
  • Solvent interactions: It is likely to be more soluble in organic solvents like ethanol, methanol, and chloroform, which can stabilize nonpolar regions of the molecule.
  • Temperature dependence: Like many organic compounds, the solubility of C21H27NO may increase with temperature, making it crucial to consider temperature effects in solubility studies.

In summary, the solubility of 6-(dimethylamino)-4,4-diphenyl-heptan-3-one is a complex interplay of its polar and nonpolar interactions. This dual nature can create interesting dynamics in various solvents. As always, careful experimentation is necessary to fully characterize its solubility in different environments.

Interesting facts

Interesting Facts about 6-(Dimethylamino)-4,4-diphenyl-heptan-3-one

This fascinating compound, often referred to as a member of the ketone family, exhibits an intricate structure that piques the interest of chemists and students alike. Here are some intriguing aspects of 6-(dimethylamino)-4,4-diphenyl-heptan-3-one:

  • Functional Diversity: The presence of both ketone and amine functional groups in its structure makes this compound a candidate for various chemical reactions and transformations.
  • Synthetic Versatility: This compound can serve as a building block for creating more complex organic molecules, thanks to its rich functional groups and potential for further derivatization.
  • Applications: Compounds with similar structures are often explored in pharmaceutical research and development. Their biological activity, particularly in medicinal chemistry, opens avenues for therapeutic applications.
  • Colorimetric Reactions: The aromatic rings in its structure may lead to interesting colorimetric properties, making it valuable in analytical chemistry for detecting specific analytes.
  • Stereochemistry: With its chiral centers (specifically at the heptane backbone), the compound's stereochemistry could lead to different isomeric forms, each potentially possessing unique physical and chemical properties.

As scientists continue to investigate compounds like this, the exploration of their properties can significantly enhance our understanding of organic chemistry and its applications in real-world scenarios. As the quote goes, "Science is the poetry of reality." The beauty in compounds like 6-(dimethylamino)-4,4-diphenyl-heptan-3-one exemplifies this sentiment, showcasing the elegance and complexity of molecular design.

Synonyms
methadone
dl-Methadone
Diaminon
Dolophin
Phenadone
Heptadone
Amidone
Ketalgin
Methadon
Adanon
76-99-3
Physeptone
Algovetin
Heptanon
Sedo-Rapide
Racemic methadone
Amidon
(+/-)-Methadone
Methadonum
Metadona
Metadone
Metasedin
(+-)-Methadone
Eptadone
Methadona
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-
Heptanon (pharmaceutical)
6-(dimethylamino)-4,4-diphenylheptan-3-one
Dolophine HCL
Methadonum [Latin]
6-Dimethylamino-4,4-diphenyl-3-heptanone
Metadona [INN-Spanish]
Methadonum [INN-Latin]
HSDB 3119
UNII-UC6VBE7V1Z
UC6VBE7V1Z
K 174
EINECS 200-996-9
A 4624
BRN 3213669
CHEBI:6807
IDS-NM-002
6-(Dimethylamino)-4,4-diphenyl-3-heptanone
DTXSID7023273
Methadonum (Latin)
Metadone [DCIT]
Metadona [Spanish]
Methadona [Spanish]
Polamidone
Metadona (INN-Spanish)
Methadonum (INN-Latin)
Methadone [INN:BAN]
Symoron
Methadone (BAN)
Fenadone (*Hydrochloride*)
Heptanon (*Hydrochloride*)
Dolophine (*Hydrochloride*)
Heptadone (*Hydrochloride*)
Levomethadon
Phenadone (*Hydrochloride*)
AN-148 (*Hydrochloride*)
DEA No. 9250
(RS)-methadones
(RS)-methadone
Methadone (l)
(plusmn)-methadone
PHY
Hoescht 10820 (*Hydrochloride*)
Mecodin (Salt/Mix)
Methadone-HCL,(-)
Polamidon (Salt/Mix)
Polamidone (Salt/Mix)
METHADONE [INN]
METHADONE [MI]
METHADONE [HSDB]
(.+/-.)-Methadone
METHADONE [VANDF]
CHEMBL651
METHADONE [WHO-DD]
SCHEMBL34140
DivK1c_000963
DTXCID003273
GTPL5458
Adanon hydrochloride (Salt/Mix)
BDBM82507
KBio1_000963
CHEBI:167309
NINDS_000963
NSC_22266
STL455106
AKOS015962259
rac-Methadone 0.1 mg/ml in Methanol
rac-Methadone 1.0 mg/ml in Methanol
DB00333
IDI1_000963
NCGC00248116-01
NCGC00248116-02
AC-16055
2-Dimethylamino-4,4-diphenyl-5-heptanone
CAS_5967-73-7
DB-053574
NS00000411
6-(dimethylamino)-4,4-diphenyl-heptan-3-one
rac-6-dimethylamino-4,4-diphenyl-3-heptanone
C07163
D08195
rac-6-(dimethylamino)-4,4-diphenylheptan-3-one
L000874
Q179996
(6RS)-6-(dimethylamino)-4,4-diphenylheptan-3-one
butane, 2-dimethylamino-4-ethylcarbonyl-4,4-diphenyl-
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (.+/-.)-
200-996-9