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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
6-(dimethylamino)-4,4-diphenyl-hexan-3-one
State
State

At room temperature, Methadone is typically found in a solid state, although pharmaceutical formulations may present it in liquid forms as well depending on the preparation.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
397.45
Boiling point (Kelvin)
670.60
General information
Molecular weight
309.45g/mol
Molar mass
309.4520g/mol
Density
0.9782g/cm3
Appearence

Methadone typically appears as a white, crystalline powder. It is often synthesized in laboratories and can be processed into pills, liquids, or powder form for medical usage.

Comment on solubility

Solubility of 6-(dimethylamino)-4,4-diphenyl-hexan-3-one

The solubility of 6-(dimethylamino)-4,4-diphenyl-hexan-3-one, a compound with a rich organic structure, can be influenced by several factors including its molecular structure, polarity, and the nature of the solvent used.

Generally, this compound is:

  • Soluble in organic solvents: It tends to dissolve well in organic solvents such as dichloromethane, ethanol, and acetone, owing to its non-polar and moderately polar character.
  • Insoluble in water: Due to its large hydrophobic phenyl groups, it exhibits limited solubility in polar solvents like water.

The solubility can vary depending on temperature and the presence of other chemical species. As a rule of thumb, the saying goes, “like dissolves like,” meaning that non-polar compounds are better solubilized in non-polar solvents. Therefore, for optimal solubility:

  • Consider using solvents with similar dipole moments.
  • Evaluate the impact of temperature, as increased temperatures can enhance solubility in many cases.

Understanding the solubility characteristics of 6-(dimethylamino)-4,4-diphenyl-hexan-3-one is crucial for applications in synthesis, formulation, and pharmaceutical development, making it an important aspect of its chemical properties.

Interesting facts

Exploring 6-(dimethylamino)-4,4-diphenyl-hexan-3-one

6-(dimethylamino)-4,4-diphenyl-hexan-3-one is a fascinating compound that captures the attention of chemists due to its unique structure and versatile applications. Here are some interesting facts worth noting:

  • Pharmaceutical Relevance: This compound has shown potential in medicinal chemistry, particularly in developing pharmacological agents due to its ability to interact with biological systems. Its structure allows it to influence various biological pathways.
  • Versatile Synthetic Use: It serves as an important intermediate in organic synthesis, especially in crafting various organic compounds—making it a valuable tool in the toolbox of synthetic chemists.
  • Colorimetric Properties: Due to the presence of the dimethylamino group, this compound exhibits distinctive colorimetric properties, which can be exploited in sensors and analytical chemistry.
  • Electronic Applications: The unique electronic characteristics imparted by its diphenyl and amino groups make it a candidate for applications in organic electronics, particularly in light-emitting diodes (LEDs) and organic photovoltaics.

Its synthesis and modifications provide valuable insight into structure-activity relationships (SAR)—a critical component in drug design. As one researcher noted, "Understanding the nuances of chemical compounds like 6-(dimethylamino)-4,4-diphenyl-hexan-3-one not only enlightens us about their intrinsic properties but also paves the way for innovative applications."

In conclusion, the study of 6-(dimethylamino)-4,4-diphenyl-hexan-3-one is a testament to the intricate dance between molecular structure and functionality, highlighting the endless possibilities that await in the realm of chemistry.

Synonyms
Normethadone
Mepidon
Isomethadone I
Phenyldimazone
Eucopon
Noramidone
Normedon
Hoechst 10582
Dacartil
Isoamidone I
Normetadona
Normethadonum
Normetadone
Normetadone [DCIT]
467-85-6
6-Dimethylamino-4,4-diphenyl-3-hexanone
Normetadona [INN-Spanish]
Normethadonum [INN-Latin]
Normethadone [INN:BAN:DCF]
NSC 19598
UNII-KR2L2A68XL
KR2L2A68XL
EINECS 207-401-1
HOECHST-10582
NSC-19598
IDS-NN-007
J5.915C
BRN 2748978
Normethadone (INN)
6-Dimethylamino-4,4-diphenyl-3-hexanon
1-dimethylamino-3,3-diphenyl-4-hexanone
DTXSID6057748
AI3-23988
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-
6-(dimethylamino)-4,4-diphenylhexan-3-one
NORMETHADONE [MI]
NORMETHADONE [INN]
NORMETHADONE [WHO-DD]
DTXCID7031537
4-14-00-00297 (Beilstein Handbook Reference)
6-Dimethylamio-4-diphenyl-3-hexanone
Normetadona (INN-Spanish)
Normethadonum (INN-Latin)
1,1-DIPHENYL-1-(2-DIMETHYLAMINOETHYL)-2-BUTANONE
nor-methadone
R05DA06
6-dimethylamino-4,4-diphenylhexan-3-one
207-401-1
wcjfbsyalhqbsk-uhfffaoysa-n
Desmethylmethadone
DEA No. 9635
Normethadon
NONMETHADONE
3-Hexanone,4-diphenyl-
SCHEMBL24337
CHEMBL346331
467-85-6 (free base)
CHEBI:135242
WLN: 2VXR&R&2N1&1
NSC19598
Tox21_113687
BDBM50585104
DB11609
NCGC00249911-01
CAS-467-85-6
NS00008934
D07384
Q1218578
propane, 1-dimethylamino-3-ethylcarbonyl-3,3-diphenyl-