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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one
State
State

Methadone is commonly found in solid form. It is primarily distributed as tablets or oral solutions for medicinal use.

Melting point (Celsius)
235.20
Melting point (Kelvin)
508.35
Boiling point (Celsius)
397.20
Boiling point (Kelvin)
670.35
General information
Molecular weight
309.45g/mol
Molar mass
309.4500g/mol
Density
0.9800g/cm3
Appearence

Methadone is typically available as a white, crystalline powder. It is also available in the form of a colorless solution when dissolved in appropriate solvents.

Comment on solubility

Solubility of 6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one

The solubility of 6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one in various solvents can provide insightful information regarding its chemical behavior and applications. Factors influencing solubility include:

  • Polarity: The presence of dimethylamino groups typically increases the polarity of organic compounds, potentially enhancing solubility in polar solvents such as water and alcohols.
  • Hydrophobic Groups: The large diphenyl group may create hydrophobic characteristics, making the compound less soluble in highly polar solvents but possibly more soluble in non-polar solvents like hexane or toluene.
  • Temperature: Solubility can dramatically change with temperature; hence, analyzing the compound's solubility at various temperatures is crucial for applications.

In general, it can be expected that:

  • The compound may exhibit moderate solubility in organic solvents.
  • It might have low solubility in water due to the hydrophobic nature of the diphenyl moiety.
  • Combination solvents could enhance solubility, where both polar and non-polar components are present.

Ultimately, understanding the solubility of this compound is essential for its utilization in synthetic pathways and formulations, as solubility plays a critical role in reactivity and accessibility in chemical processes.

Interesting facts

Interesting Facts about 6-(Dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one

This compound, known for its intriguing structure and properties, is a member of the ketone family. It holds significant interest in various fields of chemistry, particularly in organic synthesis and medicinal chemistry. Here are some fascinating insights about this compound:

  • Structure and Functionality: The presence of the dimethylamino group is particularly notable, as it enhances the compound's nucleophilic character. This allows for the potential to act as a reactant in various chemical reactions, paving the way for new synthetic pathways.
  • Pharmaceutical Potential: Compounds containing dimethylamino moieties are frequently investigated for their pharmacological properties. They've been linked to activities such as antidepressant and anti-inflammatory effects, making them valuable in the development of therapeutic agents.
  • Synthetic Versatility: The compound's unique arrangement of substituents offers opportunities for chemists to explore reaction mechanisms. It serves as an excellent model for studying stereochemistry and reaction dynamics in organic synthesis.
  • Colorimetric Applications: Certain derivatives of related compounds have been utilized in colorimetric assays, where a color change indicates the presence of specific analytes—showcasing the utility of such compounds beyond mere synthesis.
  • Research Impact: Ongoing research into this compound and its derivatives continues to yield new insights into both fundamental chemical principles and applied sciences, emphasizing its relevance in modern chemistry.

In summary, 6-(dimethylamino)-5-methyl-4,4-diphenyl-hexan-3-one is more than just a compound; it represents a bridge between basic research and practical application in medicinal chemistry. Its distinctive features and properties undeniably mark it as a molecule worthy of further exploration.

Synonyms
Isomethadone
Isomethadone II
Isoamidone II
Isoamidone
Isadanone
Isometadona
Isometadone
Win 1783
Isomethadonum
Isometadone [DCIT]
466-40-0
Win-1783
Isometadona [INN-Spanish]
Isomethadonum [INN-Latin]
Isomethadone [INN:BAN:DCF]
6-Dimethylamino-5-methyl-4,4-diphenyl-3-hexanone
12L95QD6KV
IDS-NI-001
1,1-Diphenyl-1-(dimethylaminoisopropyl)butanone-2
ISOMETHADONE [MI]
ISOMETHADONE [INN]
3-HEXANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-5-METHYL-
ISOMETHADONE [WHO-DD]
DTXSID40861955
Isomethadone (INN)
Isometadona (INN-Spanish)
Isomethadonum (INN-Latin)
3-Hexanone, 6-(dimethylamino)-5-methyl-4,4-diphenyl-
METHADONE HYDROCHLORIDE IMPURITY D [EP IMPURITY]
LEVOMETHADONE HYDROCHLORIDE IMPURITY D [EP IMPURITY]
METHADONE HYDROCHLORIDE IMPURITY D (EP IMPURITY)
LEVOMETHADONE HYDROCHLORIDE IMPURITY D (EP IMPURITY)
6-(Dimethylamino)-5-methyl-4,4-diphenyl-3-hexanone
DTXCID00810803
dl-Isomethadone
NIOSH/MP1931000
MP19310000
dl-6-(Dimethylamino)-4,4-diphenyl-5-methyl-3-hexanone
3-Hexanone, 6-(dimethylamino)-4,4-diphenyl-5-methyl-, (RS)-
UNII-12L95QD6KV
Isomethadon
DEA No. 9226
Liden (l-form)
Isomethadone dl-form
SCHEMBL24513
CHEMBL2107418
CHEBI:135321
IFKPLJWIEQBPGG-UHFFFAOYSA-N
ISOMETHADONE DL-FORM [MI]
AAA56110
HY-U00140
NSC117867
CS-7177
NSC-117867
D12676
Q6086074