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thioflavin T

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Identification
Molecular formula
C17H19N2O
CAS number
2390-54-7
IUPAC name
6-ethoxy-2-[5-(6-ethoxy-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole
State
State

At room temperature, thioflavin T is a solid. It is typically handled as a powder when used for scientific and industrial applications.

Melting point (Celsius)
713.65
Melting point (Kelvin)
986.80
Boiling point (Celsius)
777.65
Boiling point (Kelvin)
1 050.80
General information
Molecular weight
476.61g/mol
Molar mass
479.6210g/mol
Density
1.9809g/cm3
Appearence

Thioflavin T appears as a yellowish powder. It is often used in biology and medicinal chemistry as a fluorescent dye to stain proteins and amyloid fibrils, which gives it a bright fluorescence under the appropriate conditions.

Comment on solubility

Solubility of 6-ethoxy-2-[5-(6-ethoxy-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole

The solubility characteristics of 6-ethoxy-2-[5-(6-ethoxy-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole present interesting insights for researchers and chemists. This compound can be classified based on its functional groups and molecular structure, influencing its interaction with solvents.

In general, the solubility can be summarized as follows:

  • Polar solvents: The presence of the benzothiazole moiety and ethoxy groups can enhance solubility in polar solvents such as water and methanol, though the degree of solubility may vary.
  • Nonpolar solvents: The aromatic structure suggests that the compound may also be solubilized in nonpolar solvents like hexane or benzene.
  • Temperature dependence: Solubility is often temperature-dependent; therefore, it may be necessary to conduct temperature variation experiments to ascertain optimal solubility conditions.

Understanding the solubility of this compound is crucial as it affects its application and reactivity in various chemical processes. As a general rule, like dissolves like, meaning that the nature of the solvent greatly influences the solubility of this complex organic molecule. For future studies, it is advisable to explore the interactions between this compound and various solvents to fully characterize its solubility profile.

Interesting facts

Interesting Facts about 6-Ethoxy-2-[5-(6-ethoxy-3-methyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-3-methyl-1,3-benzothiazole

This fascinating chemical compound, rich in its structural complexity, boasts a unique combination of functional groups that contribute to its intriguing properties. Here are some key points to contemplate:

  • Pharmacological Potential: Compounds featuring benzothiazole moieties have shown considerable promise in medicinal chemistry. They have been studied for their antitumor, antimicrobial, and anti-inflammatory activities, making this compound a candidate for further pharmacological exploration.
  • Fluorophore Characteristics: The structural arrangement of the ethoxy and benzothiazole units may allow this compound to function as a fluorescent probe, which can be used in various biochemical assays and imaging applications.
  • Versatile Reactivity: The presence of the penta-2,4-dienylidene moiety indicates potential for engaging in various types of chemical reactions, including Diels-Alder reactions and Michael additions, which are fundamental in organic synthesis.
  • Synthetic Challenges: The synthesis of such complex compounds often requires advanced techniques in organic chemistry, including multi-step synthesis, protecting group strategies, and careful consideration of stereochemistry.
  • Applications in Material Science: Beyond biology, compounds like this one might find applications in material science, particularly in designing organic semiconductors or dye-sensitized solar cells due to their unique electronic properties.

This compound not only exemplifies the beauty of organic synthesis but also highlights the interconnectivity of chemistry, biology, and material science. As we delve deeper into its properties and potential applications, we may uncover new pathways for innovation!