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Berberine

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Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
State
State

At room temperature, berberine is typically in a crystalline solid state.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.36g/mol
Molar mass
336.3610g/mol
Density
1.3209g/cm3
Appearence

Berberine typically appears as a yellow crystalline compound. It has a characteristic bright yellow color which makes it distinctive among other alkaloids.

Comment on solubility

Solubility of 6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium

The solubility of 6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium can be quite complex due to its unique chemical structure. Various factors influence its solubility in different solvents, making it a subject of interest for chemists. Here are some key points to consider:

  • Polarity: The presence of the dioxole and methoxy groups indicates that this compound may exhibit polar characteristics. This can lead to higher solubility in polar solvents such as water and alcohols.
  • Hydrogen bonding: The functional groups may engage in hydrogen bonding, enhancing solubility in solvents that can form these interactions.
  • Temperature Effects: Generally, solubility can increase with temperature; hence, increasing the temperature of the solvent might improve the dissolution of this compound.
  • Concentration of solute: The solubility will also depend on the concentration at which the solute can remain dissolved without precipitating.

In summary, while specific solubility data for this compound may be required to draw definitive conclusions, the combination of polar functional groups and potential hydrogen bonding interactions suggests that it could have moderate to good solubility in appropriate polar solvents. As with many compounds, empirical testing would provide the most accurate insights into its solubility characteristics.

Interesting facts

Exploring 6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium

The compound 6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium is a fascinating member of the isoquinoline family, known for its intriguing structure and potential applications. Here are some captivating aspects of this compound:

  • Structural Complexity: The presence of both ethyl and methoxy groups attached to a dioxolo-isoquinoline framework lends this compound a unique and complex three-dimensional shape, making it a subject of interest for theoretical and computational chemists.
  • Biological Significance: Isoquinolines, including this compound, have been studied for their numerous biological activities, such as antimicrobial, anti-inflammatory, and anticancer properties. Their ability to interact with biological targets positions them as viable candidates for drug discovery.
  • Natural Occurrence: Isoquinolines and their derivatives are often found in various plants, showcasing their potential roles in nature. Research into compounds like this one can help unravel the secrets of plant defense mechanisms and the evolutionary adaptations of phytochemicals.
  • Synthetic Chemistry: The synthesis of such compounds often involves intricate strategies in organic chemistry, demonstrating the creativity and ingenuity required to obtain compounds with specific functional groups and properties.
  • Multifunctional Use: Beyond their biological significance, this class of compounds is also explored in materials science, such as in the development of organic semiconductors and light-emitting diodes (OLEDs), showcasing their versatility.

In summary, 6-ethyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium is not just a mere chemical structure; it encapsulates the synergy between complex chemistry and potential real-world applications. As scientists continue to explore the properties and functionalities of such compounds, they unlock new opportunities in both medicinal chemistry and material science.